54534-72-4Relevant academic research and scientific papers
(Benzoylphenyl)piperidines: A new class of immunomodulators
Bellamy,Chazan,Dodey,Dutartre,Ou,Pascal,Robin
, p. 1545 - 1552 (2007/10/02)
A series of (benzoylphenyl)piperidines has been synthesized and evaluated for activity as immunomodulators. Several of these compounds show good activity in primary screening on the basis of the lymphocytes mitogenic response to Con A, PHA, and PWM. A chloro group in position 4 of the benzoyl moiety as well as an amino group (or a carbamate derivative) para to the piperidine nucleus seems to be essential for activity. The depicted compounds may be considered as the first examples of a new series of immunomodulators.
Pyrazolobenzazepines
-
, (2008/06/13)
There are presented compounds of the formulas STR1 wherein R1 is hydrogen or lower alkyl; R2 and R3 are selected from the group consisting of hydrogen, lower alkyl, C2 to C7 carboxylic acids, hydroxy
