545342-37-8Relevant academic research and scientific papers
Nitrogen chirality via the sterical veto of N inversion
Usachev, Sergey V.,Nikiforov, Grygorii A.,Strelenko, Yurii A.,Chervin, Ivan I.,Lyssenko, Konstantin A.,Kostyanovsky, Remir G.
, p. 136 - 139 (2003)
Novel cyclic hydrazines 4-8 with sterically hindered (4, 6, 7) or arrested (5, 8) nitrogen inversion were synthesised; pyrazolydine 5 was separated into enantiomers by chiral chromatography; the crystal structures of salts 5a and 5b were studied by X-ray
Sterically hindered nitrogen inversion in five-membered cyclic hydrazines
Usachev, Sergey V.,Nikiforov, Grygorii A.,Strelenko, Yurii A.,Belyakov, Pavel A.,Chervin, Ivan I.,Kostyanovsky, Remir G.
, p. 189 - 193 (2007/10/03)
We found that (PriNH)2 with MeCHO form only pyrazoline 1 because of the competitive crotonization of the latter followed by reaction with hydrazine; pyrazoline 2, pyrazolidinones 6 and 9, pyrazolidinol 8 and pyrazolidine 7, in which the inversion of nitrogen atoms is hindered by bulky PriN substituents, were prepared for the first time, and the inversion barriers were determined.
