54535-14-7

Basic information

• Product Name: 4-Isoxazolecarboxylicacid,2,5-dihydro-5-oxo-,ethylester(9CI)
• Synonyms: 4-Isoxazolecarboxylicacid,2,5-dihydro-5-oxo-,ethylester(9CI);4-Isoxazolecarboxylic acid, 2,5-dihydro-5-oxo-, ethyl ester
• CAS NO: 54535-14-7
• Molecular Formula: C₆H₇NO₄
• Molecular Weight: 157.12
• Product Categories: OXAZOLE
• Mol File: 54535-14-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 222.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.334±0.06 g/cm3(Predicted)
• PKA: -7.36±0.40(Predicted)
• CAS DataBase Reference: 4-Isoxazolecarboxylicacid,2,5-dihydro-5-oxo-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolecarboxylicacid,2,5-dihydro-5-oxo-,ethylester(9CI)(54535-14-7)
• EPA Substance Registry System: 4-Isoxazolecarboxylicacid,2,5-dihydro-5-oxo-,ethylester(9CI)(54535-14-7)

Safety Data

• Hazardous Substances Data: 54535-14-7(Hazardous Substances Data)

Upstream product

• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 100422-75-1 ethyl 2-(benzothiazol-2-yl)-5-oxo-2,5-dihydroisoxazole-4-carboxylate 
• 105-56-6 ethyl 2-cyanoacetate 
• 64-17-5 ethanol 
• 141-82-2 malonic acid 
• 7664-41-7 ammonia 
• 15719-64-9 methylammonium carbonate 
• 1314307-74-8 ethyl 5-formyl-3-hydroxy-10-methyl-1-oxo-1H-pyrimido[1,2-a]quinoline-2-carboxylate 
• 1314307-52-2 ethyl 2-(3-formyl-8-methylquinolin-2-yl)-5-oxo-2,5-dihydroisoxazole-4-carboxylate 
• 56355-51-2 ethyl 2-phenoxy-thiazole-5-carboxylate 
• 212002-90-9 2-[(S)-1-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-2-phenyl-ethyl]-oxazole-5-carboxylic acid ethyl ester 
• 212002-91-0 2-((S)-1-Amino-2-phenyl-ethyl)-oxazole-5-carboxylic acid ethyl ester 
• 634923-07-2 (S)-ethyl 2-[2-(4-benzyloxyphenyl)-1-phthalimidoethyl]oxazole-5-carboxylate 
• 634923-08-3 (S)-ethyl 2-[1-amino-2-(4-benzyloxyphenyl)ethyl]-1,3-oxazole-5-carboxylate 
• 634923-04-9 (S)-ethyl 5-oxo-2-[3-(4-benzyloxyphenyl)-2-phthalimidopropanoyl]-2,5-dihydroisoxazole-4-carboxylate 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2

The present invention relates to compounds of formula I: in which Y1, Y2, R1, R2 and R3 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.