54537-47-2

Usage

Uses

Used in Organic Synthesis:
N,N-Dimethyl-α-bromopropionamide is used as a reagent in organic synthesis for the preparation of amides, esters, and other functionalized compounds. Its reactivity allows for the formation of various organic compounds, contributing to the advancement of chemical research and development.
Used in Pharmaceutical Industry:
N,N-Dimethyl-α-bromopropionamide is used as a precursor in the manufacture of pharmaceuticals and biologically active compounds. Its role in the synthesis of these compounds is crucial for the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, N,N-Dimethyl-α-bromopropionamide is employed as an intermediate in the synthesis of various agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals.
Safety Precautions:
It is important to handle N,N-Dimethyl-α-bromopropionamide with care, as it is corrosive and may cause irritation to the skin, eyes, and respiratory system. Proper safety measures should be taken during its use to minimize potential health risks.

Upstream product

• 563-76-8 α-bromopropionyl bromide 
• 124-40-3 dimethyl amine 
• 7148-74-5 2-Bromopropionyl chloride 
• 7623-16-7 3-bromopropionyl bromide 
• 506-59-2 N,N-dimethylammonium chloride 

Downstream Products

• 19386-62-0 2-(2,6-Dimethyl-phenylamino)-N,N-dimethyl-propionamide 
• 142563-82-4 methyl 4-<<5--1-<1-(N,N-dimethylcarbamoyl)ethyl>indol-3-yl>methyl>-3-methoxybenzoate 
• 71364-46-0 α-phenylthio-N,N-dimethylpropionamide 
• 90425-35-7 N,N-dimethyl-2-phenylsulphinylacrylamide 
• 90425-32-4 2-Benzenesulfinyl-N,N-dimethyl-propionamide 
• 90425-34-6 2-Benzenesulfinyl-N,N-dimethyl-2-phenylselanyl-propionamide 
• 90425-55-1 (2S,5R,6R)-6-((E)-2-Dimethylcarbamoyl-vinyl)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 90425-53-9 (2S,5R)-6-Bromo-6-((E)-2-dimethylcarbamoyl-vinyl)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 90425-56-2 (2S,5R)-6-Bromo-6-((E)-2-dimethylcarbamoyl-vinyl)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 90425-52-8 (2S,5R)-6-(2-Benzenesulfinyl-2-dimethylcarbamoyl-ethyl)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 197145-53-2 3-(3-methoxyphenyl)-N,N,2-trimethylpent-3-enamine 
• 58235-04-4 3-Methyl-but-2-enoic acid (1-dimethylcarbamoyl-ethyl)-(2,6-dimethyl-phenyl)-amide 

Relevant academic research and scientific papers

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

PROCESS FOR THE PREPARATION OF 3-[(1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL]-PHENOL

A process for the preparation of a compound of formula (I) and of a acid salt (T) wherein R1 is selected from the group consisting of alkyl, aryl, cycloalkyl, heteroalkyl, heteroaryl and heterocycloalkyl, R2 and R3, are, independently of each other, selected from the group consisting of alkyl, aryl, cycloalkyl, heteroalkyl, heteroaryl and heterocycloalkyl, R4, R5, R6 and R7, are independently of each other, selected from the group consisting of H, alkyl, aryl, cycloalkyl, heteroalkyl, heteroaryl and heterocycloalkyl, and wherein the acid salt is a 2,3-Ditoluoyl tartaric acid salt, 2,3-Dibenzoyl tartaric acid salt, 2,3-Dianisoyl tartaric acid salt, 2,3-Dibenzoyl tartaric acid mono(dimethylamide) salt or a mixture of two or more thereof, wherein the tartaric acid salt (T) of the compound of formula (I) contains at least 90 % by weight of the tartaric salt of the compound of formula (Ia) based on the total weight of the acid salt of the compound of formula (I).

CYANOARYLAMINES

The present invention relates to a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, or a combination thereof; wherein R°, R1, R1', R2, R2', R3 and n are defi

Preparation and Properties of Substituted 6&β-Vinylpenicillanic Acids

Routes to the title compounds are described, either using the selective addition of thiols to the known 6-allylidenepenicillanic acids or by the conjugate addition of Grignard derivatives, derived from 6,6-dibromopenicillanates, to substituted acrylates and acrylamides, followed by stereoselective reduction of the remaining 6-bromo-group to produce the 6β-substituted penicillanates.The 6β-derivatives containing the acryloyl side-chain were relatively unstable and readily underwent intramolecular rearrangement to the corresponding thiazepinones.