54537-88-1Relevant academic research and scientific papers
A SIMPLE SINTHESIS OF TROPONES AND RELATED COMPOUNDS
Barbier, Michael,Barton, Derek H. R.,Devys, Michel,Topgi, Ravindra Satish
, p. 5031 - 5038 (2007/10/02)
Cyclohexa-2,4- and 2,5-dienones bearing position 2 or 4 a dihalomethyl group (halogen = chlorine or bromine) are smoothly reduced by tri-butyltin hydride to furnish appropriately substituted tropones.Modification of the substituents permits access to a tropolone and to less substituted tropones.The mechanism of this ring expansion process has been discussed.
A Simple Synthesis of the Tropone Nucleus
Barbier, Michel,Barton, Derek H. R.,Devys, Michel,Topgi, Ravindra Satish
, p. 743 - 744 (2007/10/02)
Reduction of suitably substituted dichloro- or dibromo-methylcyclohexadienones with tributyltin hydride affords tropones (or tropolones) in medium to excellent yield; ortho- and para-substituted cyclohexadienones afford the same tropone.
