5454-07-9

Basic information

• Product Name: N-(1-piperidinyl)benzamide
• Synonyms: N-(1-piperidinyl)benzamide
• CAS NO: 5454-07-9
• Molecular Formula: C₁₂H₁₆N₂O
• Molecular Weight: 204.26824
• Mol File: 5454-07-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.12g/cm³
• Refractive Index: 1.577
• CAS DataBase Reference: N-(1-piperidinyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-piperidinyl)benzamide(5454-07-9)
• EPA Substance Registry System: N-(1-piperidinyl)benzamide(5454-07-9)

Safety Data

• Hazardous Substances Data: 5454-07-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16N2O/c15-12(11-7-3-1-4-8-11)13-14-9-5-2-6-10-14/h1,3-4,7-8H,2,5-6,9-10H2,(H,13,15)

Upstream product

• 2213-43-6 1-Aminopiperidine 
• 98-88-4 benzoyl chloride 
• 35990-31-9 N-(3,6-dihydro-2H-pyridin-1-yl)-benzamide 
• 126216-67-9 N-(2,6-Bis-benzotriazol-1-yl-piperidin-1-yl)-benzamide 
• 93-58-3 benzoic acid methyl ester 
• 111-29-5 1 ,5-pentanediol 
• 613-94-5 benzoic acid hydrazide 
• 111-30-8 Glutaraldehyde 

Downstream Products

• 100138-96-3 5-(N'-benzoyl-N-nitroso-hydrazino)-valeric acid 
• 100134-97-2 1-benzoylamino-piperidin-2-one 

Relevant articles and documents

Direct Catalytic Symmetrical, Unsymmetrical N,N-Dialkylation and Cyclization of Acylhydrazides Using Alcohols

Herein, direct N,N-dialkylation of acylhydrazides using alcohols is reported. This catalytic protocol provides one-pot synthesis of both symmetrical and unsymmetrical N,N-disubstituted acylhydrazides using an assortment of primary and secondary alcohols w

A Novel and Versatile Synthesis of 1-Alkyl-, 1-Aryl-, 1-(Alkylamino)-, or 1-Amido-Substituted and of 1,2,6-Trisubstituted Piperidines from Glutaraldehyde and Primary Amines or Monosubstituted Hydrazines

Various primary amines and 1-mono- and 1,1-disubstituted hydrazines were converted into the corresponding N-substituted piperidines in good to excellent yields via the products of double condensations with benzotriazole and glutaraldehyde.Reduction of the 2,6-bis(benzotriazolyl) N-substituted piperidines 4 and 7 with sodium borohydride in tetrahydrofuran afforded N-substituted piperidines.The benzotriazole moieties were also replaced by alkyl groups by reaction with Grignard reagents to produce 1,2,6-trisubstituted piperidines.