5454-76-2

Usage

Uses

Used in Pharmaceutical Research and Development:
2-Methylcyclopentanamine hydrochloride is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique cyclic amine structure and hydrochloride salt form contribute to its stability and solubility, making it a promising candidate for drug development.
Used in Hyperglycemia Treatment:
2-Methylcyclopentanamine hydrochloride is used as a potential prophylactic treatment for hyperglycemia. Its chemical properties allow it to be studied for its effects on blood sugar levels, offering a possible therapeutic approach to managing and preventing hyperglycemia.
Used in Central Nervous System Disorder Treatment:
2-Methylcyclopentanamine hydrochloride is used as a potential drug candidate for the treatment of central nervous system disorders. Its unique structure and properties make it a valuable compound for exploring new treatment options for neurological conditions.
Used in Medicinal Chemistry:
2-Methylcyclopentanamine hydrochloride is used as a valuable compound in the field of medicinal chemistry. Its cyclic amine structure and hydrochloride salt form provide a foundation for the development of new drugs and therapeutic agents.

InChI:InChI=1/C6H13N/c1-5-3-2-4-6(5)7/h5-6H,2-4,7H2,1H3

Relevant academic research and scientific papers

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

Regio- and stereoselective ring openings of 3-aza-2-oxabicyclo[2.2.1]hept-5-ene systems with copper catalyst-modified grignard reagents: Application to the synthesis of an inhibitor of 5-lipoxygenase

Treatment of acylnitroso hetero Diels-Alder cycloadducts 2 with organomagnesium reagents in the presence of a catalytic amount of copper induces ring opening to afford predominantly monocyclic anti-1,2-hydroxamic acids 12. Alkylmagnesium reagents were found to give superior regio- and stereoselectivities compared with vinyl and arylmagnesium reagents. This cycloadduct ring opening methodology was applied to the synthesis of a unique cyclopentenyl hydroxamic acid-based inhibitor of 5-lipoxygenase.