545400-04-2Relevant academic research and scientific papers
Stereoselective solid-phase synthesis of chiral piperidine derivatives by using an immobilized galactose auxiliary
Zech, Gernot,Kunz, Horst
, p. 787 - 790 (2003)
The fluoride-labile anchoring of a galactosylamine enabled the first stereoselective solid-phase combinatorial synthesis of didehydropiperidinones 1. The piperidine derivatives formed by asymmetric domino Mannich-Michael condensation at ambient temperatur
Synthesis of a polymer-bound galactosylamine and its application as an immobilized chiral auxiliary in stereoselective syntheses of piperidine and amino acid derivatives
Zech, Gernot,Kunz, Horst
, p. 4136 - 4149 (2007/10/03)
A 2,3,4-tri-O-pivaloylated β-D-galactopyranosyl azide bearing a hydroxy-functionalized spacer unit at the C-6 position of the galactose was synthesized and immobilized on the solid phase by using a polymer-bound chlorosilane. The azide was reduced to the
