5455-24-3

Basic information

• Product Name: 4,5-Octanedione
• Synonyms: Bibutyryl;4,5-Octadione
• CAS NO: 5455-24-3
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.2
• Mol File: 5455-24-3.mol
• Article Data: 16

Chemical Properties

• Melting Point: 14.93°C (estimate)
• Boiling Point: 168.05°C
• Flash Point: 56.5°C
• Appearance: /
• Density: 0.9340
• Vapor Pressure: 1.65mmHg at 25°C
• Refractive Index: 1.4559 (estimate)
• CAS DataBase Reference: 4,5-Octanedione(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Octanedione(5455-24-3)
• EPA Substance Registry System: 4,5-Octanedione(5455-24-3)

Safety Data

• Hazardous Substances Data: 5455-24-3(Hazardous Substances Data)

Usage

General Description

4,5-Octanedione, also known as diacetyl, is a chemical compound with the molecular formula C8H12O2. It is commonly used as a flavoring agent in food and beverages, providing a buttery or creamy taste. Despite its widespread use, diacetyl has been linked to a number of health concerns, particularly respiratory issues. It has been associated with a condition known as "popcorn lung," which is a severe and irreversible lung disease found in workers at microwave popcorn factories who have been exposed to high levels of diacetyl. Due to these health risks, efforts have been made to limit the use of diacetyl in food and beverage products.

InChI:InChI=1/C8H14O2/c1-3-5-7(9)8(10)6-4-2/h3-6H2,1-2H3

Upstream product

• 105-54-4 butanoic acid ethyl ester 
• 96-09-3 styrene oxide 
• 141-75-3 butyryl chloride 
• 1942-45-6 4-Octyne 
• 122-60-1 Phenyl glycidyl ether 
• 286-20-4 cyclohexane-1,2-epoxide 
• 108-24-7 acetic anhydride 
• 123-72-8 butyraldehyde 
• 201230-82-2 carbon monoxide 
• 75-19-4 cyclopropane 
• 60-29-7 diethyl ether 
• 142-96-1 dibutyl ether 
• 67-56-1 methanol 
• 592-99-4 4-octene 

Downstream Products

• 3639-22-3 2,2-dipropylglycolic acid 
• 107-92-6 butyric acid 
• 496-77-5 butyroin 
• 22520-41-8 meso-4,5-octanediol 
• 22520-40-7 syn-4,5-octanediol 
• 86628-42-4 3-p-Nitrophenyl-5,6-di-n-propylimidazo<2,1-b>thiazole 
• 86628-34-4 3-Biphenyl-4-yl-5,6-dipropyl-imidazo[2,1-b]thiazole 
• 86628-41-3 2-p-Nitrophenacylthio-4,5-di-n-propylimidazole 
• 86628-29-7 1-Biphenyl-4-yl-2-(4,5-dipropyl-1H-imidazol-2-ylsulfanyl)-ethanone 
• 86628-35-5 3-Phenyl-5,6-dipropyl-imidazo[2,1-b]thiazole 
• 86628-30-0 2-(4,5-Dipropyl-1H-imidazol-2-ylsulfanyl)-1-phenyl-ethanone 
• 25379-20-8 2-phenylindolizine 
• 83260-60-0 2,3-Dipropyl-quinolizinylium; bromide 

Relevant articles and documents

Sol-gel synthesis of ceria-zirconia-based high-entropy oxides as high-promotion catalysts for the synthesis of 1,2-diketones from aldehyde

Efficient Lewis-acid-catalyzed direct conversion of aldehydes to 1,2-diketones in the liquid phase was enabled by using newly designed and developed ceria–zirconia-based high-entropy oxides (HEOs) as the actual catalysts. The synergistic effect of various cations incorporated in the same oxide structure (framework) was partially responsible for the efficiency of multicationic materials compared to the corresponding single-cation oxide forms. Furthermore, a clear, linear relationship between the Lewis acidity and the catalytic activity of the HEOs was observed. Due to the developed strategy, exclusively diketone-selective, recyclable, versatile heterogeneous catalytic transformation of aldehydes can be realized under mild reaction conditions.

Product selectivity in the electroreduction of thioesters

The electroreduction of differently substituted aromatic and aliphatic thioesters (RCOSR′) led to regioselective reactions depending on the nature of the substituents. Thus, the cleavage between the carbonyl group and the SR′ group afforded α-diketones an

Lewis acid assisted permanganate oxidations

Lewis acids combine with permanganate in acetone solutions to form a complex that has enhanced oxidizing capabilities. The use of Lewis acids under these conditions to promote permanganate oxidations is superior to the use of Bronsted acids because the latter promote enolization of the solvent and subsequent unproductive reduction of the oxidant. The products obtained from a variety of alkenes, alkynes, arenes, sulfides, alcohols and ethers have been identified and probable reaction mechanisms proposed.