5456-76-8

Usage

Chemical class

Nitrofuran compound

Physical state

Yellow solid

Potential applications

Pharmaceutical and agricultural industries

Known properties

Antimicrobial and antiparasitic

Biological activities

May have similar biological activities to other nitrofuran compounds

Concerns

Potential toxicity and carcinogenicity

Use restrictions

Restricted in food production in many countries

Further research

Needed to fully understand potential uses and risks

Upstream product

• 3194-15-8 2-propionylfuran 
• 609-39-2 2-nitrofuran 
• 600-25-9 1-chloro-1-nitropropane 

Relevant academic research and scientific papers

Vicarious nucleophilic substitution of hydrogen in nitroderivatives of five-membered heteroaromatic compounds

Nitro derivatives of thiophene, furan and pyrrole react with carbanions containing leaving groups giving products of replacement of hydrogen with functionalized alkyl substituents. Many specific features of this reaction are discussed.

ROTATIONAL ISOMERS OF THE RADICAL-ANIONS OF 2-CARBONYL-CONTAINING DERIVATIVES OF 5-NITROFURAN

The radical-anions of 2-carbonyl-containing derivatives of 5-nitrofuran were obtained by electrochemical generation.Their ESR spectra indicate the existence of a mixture of O,O-cis and O,O-trans rotational isomers.The parameters of the isomers were identified by INDO calculations.The more polar form (the cis isomer) is more stable in polar media.