5456-92-8

Usage

Uses

Used in Pharmaceutical Research:
(5Z)-5-imino-4-[(4-methylphenyl)hydrazono]-1-phenyl-4,5-dihydro-1H-pyrazol-3-amine is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential biological activities. Its unique structure allows for the development of new drugs, particularly in the areas of anti-inflammatory and anti-cancer medications.
Used in Organic Synthesis:
In the field of organic synthesis, (5Z)-5-imino-4-[(4-methylphenyl)hydrazono]-1-phenyl-4,5-dihydro-1H-pyrazol-3-amine serves as a valuable building block for creating more complex molecules with diverse applications. Its reactivity and functional groups make it a versatile component in the synthesis of a wide range of organic compounds.
Used in Drug Development:
(5Z)-5-imino-4-[(4-methylphenyl)hydrazono]-1-phenyl-4,5-dihydro-1H-pyrazol-3-amine is used as a starting material for the development of new drugs, thanks to its structural features and potential pharmacological properties. Further research and studies are necessary to fully understand its potential uses and effects in the pharmaceutical industry.
Used in Chemical Research:
(5Z)-5-imino-4-[(4-methylphenyl)hydrazono]-1-phenyl-4,5-dihydro-1H-pyrazol-3-amine is also utilized in chemical research to study the properties of pyrazole derivatives and their interactions with other molecules. Understanding these interactions can lead to the discovery of new reactions and applications in various chemical processes.

Upstream product

• 106-49-0 p-toluidine 
• 100-63-0 phenylhydrazine 
• 109-77-3 malononitrile 
• 40257-94-1 2-[2-(4-methylphenyl)hydrazono]malononitrile 

Relevant academic research and scientific papers

Synthesis, characterization and biological activity of some pyrazole-pyrazolone derivatives

SIX heterocyclic compounds were synthesized based on pyrazole and pyrazolone rings. The chemical structures of the synthesized compounds were characterized by using: elemental analysis, FTIR, 1H-NMR, 13C-NMR and Mass spectra. The compounds were evaluated for their activity against gram +ve, gram-ve bacteria and fungi. The antimicrobial assessment showed the high activity of compounds I and VI.

Synthesis, characterization and biological activity of some pyrazole-pyrazolone derivatives

SIX heterocyclic compounds were synthesized based on pyrazole and pyrazolone rings. The chemical structures of the synthesized compounds were characterized by using: elemental analysis, FTIR, 1H-NMR, 13C-NMR and Mass spectra. The compounds were evaluated for their activity against gram +ve, gram -ve bacteria and fungi. The antimicrobial assessment showed the high activity of compounds I and VI.

Synthesis, absorption properties and biological evaluation of some novel disazo dyes derived from pyrazole derivatives

In this study, 20 novel disazo dyes containing pyrazole derivatives were synthesized by a convenient method. Diazotized aniline and some aniline derivatives were reacted with malononitrile to give 2-arylazomalononitrile derivatives 1(a-e). The synthesized 2-arylazomalononitrile derivatives were reacted with hydrazine and phenyl hydrazine to afford the corresponding 3,5-diamino-4-arylazo-1 H-pyrazole 2(a-e) and 3,5-diamino-4-arylazo-1-phenylpyrazole 3(a-e). Diazotized compounds of 2(a-e)and 3(a-e) reacted with ethylacetoacetate to give 4-arylazo-3-amino-1 H-pyrazole-5-ylazo-ethylacetoacetate 4(a-e) and 4-arylazo-3-amino-1-phenylpyrazole-5-ylazo-ethylacetoacetate 7(ae). The obtained 4(a-e) and 7(a-e) were reacted with hydrazine and phenyl hydrazine to give disazo dyes 5(a-e), 6(a-e), 8(a-e) and 9(a-e), respectively. The synthesized disazo dyes were characterized by spectroscopic techniques as well as elemental analysis. The solvatochromic behaviours of these dyes in various solvents were examined. Acid-base effects on the absorption maxima of the dyes were also reported. Antimicrobial activities of the synthesized novel disazo dyes were investigated.