5457-57-8 Usage
Uses
Used in Pharmaceutical Industry:
(1R,2S)-2-sulfanylcyclopentanol is used as a synthetic intermediate for the production of pharmaceuticals. Its chiral nature makes it an important starting material for the preparation of enantiomerically pure compounds, which are crucial for drug development and ensuring the desired therapeutic effects.
Used in Agrochemical Industry:
(1R,2S)-2-sulfanylcyclopentanol is also utilized as a synthetic intermediate in the agrochemical industry. It aids in the synthesis of various agrochemicals, contributing to the development of effective products for agricultural applications.
Used in Asymmetric Synthesis:
(1R,2S)-2-sulfanylcyclopentanol is used as a building block in asymmetric synthesis. Its unique stereochemistry allows for the selective formation of specific enantiomers, which is vital for creating biologically active molecules with desired properties.
Used in Natural Product Synthesis:
(1R,2S)-2-sulfanylcyclopentanol is employed as a building block in the synthesis of natural products. Its structural features make it a valuable component in creating complex organic molecules that can be found in nature and have potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 5457-57-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,5 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5457-57:
(6*5)+(5*4)+(4*5)+(3*7)+(2*5)+(1*7)=108
108 % 10 = 8
So 5457-57-8 is a valid CAS Registry Number.
5457-57-8Relevant academic research and scientific papers
Catalytic asymmetric synthesis of thiols
Monaco, Mattia Riccardo,Prvost, Sbastien,List, Benjamin
, p. 16982 - 16985 (2015/02/18)
The synthesis of enantiopure thiols is of significant interest for industrial and academic applications. However, direct asymmetric approaches to free thiols have previously been unknown. Here we describe a novel organocascade that is catalyzed by a confined chiral phosphoric acid and furnishes O-protected β-hydroxythiols with excellent enantioselectivities. The method relies on an asymmetric thiocarboxylysis of meso-epoxides, followed by an intramolecular trans-esterification reaction. By varying the reaction conditions, the intermediate thioesters can also be obtained chemoselectively and enantioselectively.
