5458-99-1Relevant articles and documents
Bis[N-(2-hydroxyethyl)-β-alaninato]-copper(II)
Pestov, Alexander V.,Peresypkina, Eugenia V.,Virovets, Alexander V.,Podberezskaya, Nina V.,Yatluk, Yury G.,Skorik, Yury A.
, p. m510-m512 (2005)
The CuII ion in the title complex, [Cu(C5H 10NO3)2] or [Cu(He-ala)2] [He-ala = W-(2-hydroxyethyl)-β-alaninate], resides at the inversion centre of a square bipyramid comprised of two facially arranged tridentate He-ala ligands. Each He-ala ligand binds to a CuII ion by forming one six-membered β-alaninate chelate ring in a twist conformation and one five-membered ethanolamine ring in an envelope conformation, with Cu-N = 2.017 (2) A, Cu-OCoo = 1.968 (1) A and Cu-OOH = 2.473 (2) A. The [Cu(He-ala)2] molecules are involved in a network of O-H...O and N-H...O hydrogen bonds, forming layers parallel to the (101) plane. The layers are connected into a three-dimensional structure by van der Waals interactions, so that the molecular centres form pseudo-face-centered close packing.
Cross-linked hyaluronate compounds
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Page/Page column 5, (2010/02/14)
There is disclosed a cross-linked hyaluronate compound obtained by reacting a sodium hyaluronate compound with a polfunctional aziridine compound as a cross-linking agent. The polyfunctional aziridine compound was added to hyaluronan of various molecular weights in an equivalent ratio of HA/AZ of 1:1 to 1:10, preferably, 1:3 to 1:10, more preferably, 1:3 to 1:5; most preferably 1:4 to 1:5. The polymeric hydrogel compounds obtained are useful to prevent the formation of post-operative adhesions, designing tissue engineering applications, and the like.