5460-34-4 Usage
Chemical class
Pteridines
Derivative of
Folic acid
Application
Antifolate drug
Medical uses
Treatment of certain types of cancer, rheumatoid arthritis, and psoriasis
Mechanism of action
Inhibits the enzyme dihydrofolate reductase
Enzyme involvement
Dihydrofolate reductase (DHFR)
Enzyme function
Synthesis of DNA and RNA
Effect on cells
Disrupts growth and multiplication of cancer cells and other rapidly dividing cells
Importance
Key drug in the treatment of several medical conditions
Combination therapy
Often used with other chemotherapy drugs
Check Digit Verification of cas no
The CAS Registry Mumber 5460-34-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5460-34:
(6*5)+(5*4)+(4*6)+(3*0)+(2*3)+(1*4)=84
84 % 10 = 4
So 5460-34-4 is a valid CAS Registry Number.
5460-34-4Relevant academic research and scientific papers
FLAVIN DERIVATIVES
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, (2011/02/24)
The present invention relates novel flavin derivatives and other flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. The invention also provides method of making novel flavin derivatives.
FLAVIN DERIVATIVES
-
, (2010/04/03)
The present invention relates novel flavin derivatives and other flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. The invention also provides method of making novel flavin derivatives.
