54609-18-6

Usage

Chemical structure

A pyrrole ring with a 4-ethoxyphenyl group and two methyl groups attached to it.

Usage

Commonly used in organic synthesis and research as a building block for various organic compounds.

Potential applications

Has potential applications in the pharmaceutical industry for the development of new drugs due to its structural and biological properties.

Other uses

May also have uses in the production of dyes, pigments, and other specialty chemicals.

Safety

It is important to handle this chemical with care and proper safety protocols due to its potential hazards if mishandled.

Upstream product

• 110-13-4 2,5-hexanedione 
• 156-43-4 4-Ethoxyaniline 

Downstream Products

• 1429308-98-4 3-(diphenylphosphino)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrole 
• 1429309-04-5 N-((4-(diphenylphosphoryl)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methylene)-1-phenylethanamine 
• 1429309-03-4 3-(diphenylphosphoryl)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrole 
• 1429309-02-3 3-(diphenylphosphoroselenoyl)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrole 
• 1429309-01-2 3-(diphenylphosphorothioyl)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrole 
• 1429309-00-1 borane complex of 3-(diphenylphosphino)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrole 
• 1429308-99-5 4-(diphenylphosphoryl)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde 
• 1429309-05-6 N-((4-(diphenylphosphino)-1-(4-ethoxyphenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methylene)-1-phenylethanamine 

Relevant academic research and scientific papers

Silica tungstic acid and sulphated silica tungstic acid as highly efficient solid acid catalysts for the synthesis of pyrrole derivatives

In the present study silica supported tungstic acid (STA) and sulphated silica tungstic acid (SSTA) were applied as efficient and cost-effective solid acid catalysts in the synthesis of N-substituted pyrrole derivatives via the Paal–Knorr reaction of 2,5-hexadione with aromatic and aliphatic amines at room temperature. The reaction completed in short time under mild conditions with high yield. The catalysts could be easily recovered upon reaction completion. Structures of all products were confirmed by elemental analysis, FT-IR, 1H and 13C NMR spectra.

An efficient synthesis of N-substituted pyrroles catalyzed by MgI2 etherate

We describe a convenient and useful procedure for the synthesis of various 2,5-dimethyl-N-substituted pyrrole derivatives by the addition of 2,5-hexadione with aromatic amines, heteroaromatic amines and aliphatic amines catalyzed by MgI2 etherate (MgI2·(OEt2)n) in good to excellent yields.

Sulfamic acid as efficient and reusable catalytic system for the synthesis of pyrrole, furan, and thiophene derivatives

Sulfamic acid has been utilized for the first time as an efficient and reusable catalytic system for the synthesis of heteroaromatics such as pyrrole, furan, and thiophene derivatives from 1,4-diketones. This new procedure offers significant improvements in the reaction rates and yields in a shorter reaction time and a lower reaction temperature contrasted with the reported results. The recovered catalyst can be reused for subsequent runs with only a gradual decrease in activity. The most important feature is that the reaction process is homogeneous whereas the separation process is heterogeneous, which is often seen in other catalysts, and so it is a good character for technical application.

Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives: High-affinity ligands to the α2δ subunit of voltage gated calcium channels

A novel class of 6-aryl-6H-pyrrolo[3,4-d]pyridazine ligands for the α2δ subunit of voltage-gated calcium channels has been described. Substitutions in the aryl ring of the molecule were generally not tolerated, and resulted in diminished bindin