546145-03-3

Basic information

• Product Name: N-(2-AMinoethyl)-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)acetaMide
• Synonyms: N-(2-AMinoethyl)-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)acetaMide
• CAS NO: 546145-03-3
• Molecular Formula: C9H14N4O3
• Molecular Weight: 226.23246
• Mol File: 546145-03-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: N-(2-AMinoethyl)-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-AMinoethyl)-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)acetaMide(546145-03-3)
• EPA Substance Registry System: N-(2-AMinoethyl)-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)acetaMide(546145-03-3)

Safety Data

• Hazardous Substances Data: 546145-03-3(Hazardous Substances Data)

Usage

General Description

N-(2-Aminoethyl)-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide is a chemical compound that consists of an aminoethyl group and a dioxo-dihydropyrimidinylacetamide group. It is primarily used as a pharmaceutical intermediate for the synthesis of various drugs. N-(2-AMinoethyl)-2-(5-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)acetaMide may also have potential applications in the field of medicinal chemistry, particularly in the development of new therapeutic agents. The presence of the aminoethyl and dioxo-dihydropyrimidinylacetamide groups in the structure of this chemical suggests that it could have biological activity and interactions with biological systems, making it a subject of interest for further research and investigations.

Upstream product

• 107-15-3 ethylenediamine 
• 157401-17-7 2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetonitrile 
• 20924-05-4 thymidyl acetic acid 
• 65-71-4 thymin 
• 134456-94-3 methyl (5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)ethanoate 

Relevant articles and documents

Syntheses of N-substituted thymine thioacetamides. A novel approach to site selective acylation of diaminoalkanes

A new series of N-substituted thiocarbamoyl derivatives containing histamine, tryptamine, and other moieties having at least one amino group attached to an aliphatic chain, has been synthesized from (1-thyminyl)thioacetamide in good isolated yields (69-86%). N-[2-(4-Imidazolyl)ethyl](1-thyminyl)thioacetamide was hydrolyzed to its amide on prolonged heating in water. Ammonium sulfide (20-22% solution in water) has found interesting new applications in the efficient synthesis of N-[2-(3-indolyl)ethyl](1-thyminyl)thioacetamide and site selective acylation of diaminoalkanes, starting directly from nitriles. (C) 2000 Elsevier Science Ltd.

Thymine-based near-infrared squaraine dye probe and preparation method and application thereof

The invention relates to the field of dye probe preparation, particularly to a thymine-based near-infrared squaraine dye probe and a preparation method and application thereof. The preparation method comprises taking 1-(3-dimethyl aminopropyl)-3-ethyl carbodiimide and 1-hydroxybenzothioamide as catalysts, N, N-diisopropylethylamine as organic base and dimethyl formamide as solvent to perform key reaction for producing amido bonds, and taking ethylenediamine as truss arm to link thymine and unsymmetric squaraine dyes via covalent bonds to prepare the unsymmetric thymine-based near-infrared squaraine dye probe. Existing near-infrared dye probes mainly focus on recognition of ions of Fe3+, and the thymine-based near-infrared squaraine dye probe solves the problem of selective recognition of Fe2+ and Co2+ in near-infrared absorbing areas.