5462-94-2Relevant academic research and scientific papers
Stereoselective organocatalytic oxidation of alcohols to enals: A homologation method to prepare polyenes
Chen, Xiaobei,Zhang, Yinan,Wan, Huixin,Wang, Wei,Zhang, Shilei
, p. 3532 - 3535 (2016/03/04)
A novel method for organocatalytic oxidation through oxidative enamine catalysis was developed with excellent compatibility for the direct syntheses of enals from simple saturated alcohols. By using this amine-catalyzed IBX-oxidation, a wide range of aromatic and aliphatic substituted enals were successfully generated in high yields and exclusively stereoselective E-geometry. Moreover, varying the solvents and/or the loading amounts of IBX allowed for the selective oxidation of alcohols and aldehydes. Importantly, the homologous application of this method provided a selective and efficient way of preparing various highly sensitive conjugated polyene frameworks, which are enriched in natural products.
ω-Halogeno polyenals: Preparation and application to a one-pot synthesis of polyenals from carbonyl compounds
Soullez, David,Ple, Gerard,Duhamel, Lucette
, p. 1639 - 1645 (2007/10/03)
Syntheses of 5-halogeno-2,4-dienals 1a-c are described starting either from the glutaconaldehyde potassium salt or from furan. The 5-bromopenta-2,4-dienal 1b can be transformed efficiently into homologous ω-bromo polyenals 2-4, precursors of ω-bromo polye
