54632-04-1

Basic information

• Product Name: (4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol
• Synonyms: (+)-Albicanol;(1S,4aα)-Decahydro-5,5,8aβ-trimethyl-2-methylenenaphthalene-1-methanol;(4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol;(4aα)-Decahydro-5,5,8aβ-trimethyl-2-methylenenaphthalene-1β-methanol;Albicanol
• CAS NO: 54632-04-1
• Molecular Formula: C₁₅H₂₆O
• Molecular Weight: 222.36634
• Mol File: 54632-04-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 299.3°Cat760mmHg
• Flash Point: 107.3°C
• Appearance: /
• Density: 0.95g/cm³
• Vapor Pressure: 0.00012mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: (4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol(54632-04-1)
• EPA Substance Registry System: (4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol(54632-04-1)

Safety Data

• Hazardous Substances Data: 54632-04-1(Hazardous Substances Data)

Usage

General Description

(4aα)-2-Methylene-5,5,8aβ-trimethyldecalin-1β-methanol is a complex chemical compound with a long and specific name. It is a type of alcohol, with a methanol group attached to a decalin ring structure. The presence of a methylene group and several methyl groups gives this compound its unique structure and properties. This chemical compound may have applications in various fields, including pharmaceuticals, agrochemicals, and fragrances, due to its unique structure and potential reactivity. However, due to its complexity and potential reactivity, this compound would require further study and analysis before any specific applications or uses can be determined.

InChI:InChI=1/C15H26O/c1-11-6-7-13-14(2,3)8-5-9-15(13,4)12(11)10-16/h12-13,16H,1,5-10H2,2-4H3/t12-,13-,15+/m0/s1

Upstream product

• 106-28-5 Farnesol 
• 53163-41-0 ((1S,2R,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl)methyl acetate 
• 596-85-0 (+)-manool 
• 157722-55-9 (1S,2R,4aS,8aS)-1-(tert-butyldimethylsilyloxymethyl)-decahydro-2,5,5,8a-tetramethylnaphthalen-2-ol 
• 52617-99-9 (+)-drimane-8,11-diol 
• 106-24-1 Geraniol 
• 4602-84-0 farnesol 
• 71-36-3 butan-1-ol 
• 71-41-0 pentan-1-ol 
• 53163-41-0 (+/-)-9αH-drimane-7α,11-diol 11-monoacetate 

Downstream Products

• 468-68-8 (8aS)-(-)-drimenol 
• 765950-82-1 (4aS,6aS,12bS)-2H-9,10-dibenzyloxy-11-chloro-1,3,4,4a,5,6,6a,12b-octahydro-4,4,6a,12b-tetramethyl-benzo[a]xanthene 
• 682744-27-0 (1S,4aS,8aS)-1-[(3,4-dibenzyloxy-2-chloro-6-hydroxyphenyl)-hydroxymethyl]-3H-2-methylene-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethylnaphthalene 
• 765950-78-5 (4aS,6aS,12bS)-2H-9,10-dibenzyloxy-11-chloro-1,3,4,4a,5,6,6a,12b-octahydro-6a-[(phenylseleno)methyl]-4,4,12b-trimethyl-benzo[a]xanthene 
• 682744-26-9 (1S,4aS,8aS)-1-[(3,4-dibenzyloxy-6-tert-butyldimethylsilyloxy-2-chlorophenyl)-hydroxymethyl]-3H-2-methylene-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethylnaphthalene 
• 63757-96-0 (+/-)-zonarol dimethyl ether 
• 33762-81-1 (+)-[(1S,2S,8aS)-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl]methanol 
• 510-98-5 [(1S,2R,4aS,8aS)-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl]methanol 
• 254428-62-1 Acetic acid (2,3,5,6-tetramethoxy-phenyl)-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-yl)-methyl ester 
• 254428-61-0 1S,4aS,8aS-decahydro-5,5,8a-trimethyl-2-methylene-α-(2,3,5,6-tetramethoxyphenyl)naphthalene-1-methanol 
• 254428-63-2 1-[[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-2,3,5,6-tetramethoxybenzene 

Relevant articles and documents

Enzymatic Addition of Alcohols to Terpenes by Squalene Hopene Cyclase Variants

Squalene–hopene cyclases (SHCs) catalyze the polycyclization of squalene into a mixture of hopene and hopanol. Recently, amino-acid residues lining the catalytic cavity of the SHC from Alicyclobacillus acidocaldarius were replaced by small and large hydrophobic amino acids. The alteration of leucine 607 to phenylalanine resulted in increased enzymatic activity towards the formation of an intermolecular farnesyl–farnesyl ether product from farnesol. Furthermore, the addition of small-chain alcohols acting as nucleophiles led to the formation of non-natural ether-linked terpenoids and, thus, to significant alteration of the product pattern relative to that obtained with the wild type. It is proposed that the mutation of leucine at position 607 may facilitate premature quenching of the intermediate by small alcohol nucleophiles. This mutagenesis-based study opens the field for further intermolecular bond-forming reactions and the generation of non-natural products.

Total synthesis of bioactive drimane-epoxyquinol hybrid natural products: Macrophorin A, 4′-oxomacrophorin A, and 1′-epi-craterellin A

Total synthesis of novel hybrid natural products, merosesquiterpenoids macrophorin A, 4′-oxomacrophorin A, and 1′-epi-craterellin A has been accomplished following a general strategy based on a sacrificial Diels-Alder-retroDiels-Alder approach to control regio- and stereoselectivity.

New access to sesquiterpene hydroquinones: Synthesis of (+)-ent-chromazonarol

A facile access to optically active (+)-ent-chromazonarol ent-1, isolated from the sponge Disidea pallescens, is reported from commercially available (+)-manool 4. Copyright Taylor & Francis LLC.