54646-36-5Relevant academic research and scientific papers
NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
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Page/Page column 66, (2010/04/23)
Disclosed herein are cannabinoid receptor ligands of formula (I) wherein A1, A5, Rx, X4, and z are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
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Page/Page column 28, (2010/10/19)
Disclosed herein are cannabinoid receptor ligands of formula (1) wherein Ring A and R1 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also described
Semisynthesis and acetylcholinesterase inhibitory activity of stemofoline alkaloids and analogues
Sastraruji, Kwankamol,Sastraruji, Thanapat,Pyne, Stephen G.,Ung, Alison T.,Jatisatienr, Araya,Lie, Wilford
supporting information; experimental part, p. 935 - 941 (2010/09/05)
Semisynthesis of the known Stemona alkaloids oxystemofoline (7) and methoxystemofoline (8) has been achieved starting from (11Z)-1′,2′- didehydrostemofoline (6), which confirmed their structures and absolute configurations. The synthesis of (1′R)-hydroxys
Compound having polymethine-chain structure, image forming material, planographic printing plate precursor, and image forming method using the same, method of making planographic printing plate, and planographic printing method
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Page/Page column 77-78, (2010/11/28)
A compound having, in its molecule, a polymethine chain structure containing a partial structure represented by the following formula (1-1), and an image forming material containing the same. In the formula (1-1), R1, R2, R3/su
New FBPase inhibitors for diabetes
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Page/Page column 19, (2008/06/13)
Compounds of formula as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R3 have the significance given in the application and which can be used in the form of pharmaceutical compositions.
Enantioselective synthesis of cyclic ethers through a vanadium-catalyzed resolution/oxidative cyclization
Blanc, Aurelien,Toste, F. Dean
, p. 2096 - 2099 (2007/10/03)
(Chemical Equation Presented) Two steps, one catalyst: A vanadium(v)-oxo complex with a tridentate Schiff base as an additional ligand catalyzes the title reaction which transforms racemic bishomoallylic α-hydroxyesters into trans-tetrahydropyrans (THPs)
4-PHENYLPIPERIDINE DERIVATIVES AS RENIN INHIBITORS
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Page/Page column 62-63, (2008/06/13)
Compounds of the present invention having the formula (I) exhibit inhibitory activity on the natural enzyme renin. Thus, compounds of formula (I) may be employed for the treatment of hypertension, atherosclerosis, unstable coronary syndrome, congestive heart failure, cardiac hypertrophy, cardiac fibrosis, cardiomyopathy postinfarction, unstable coronary syndrome, diastolic dysfunction, chronic kidney disease, hepatic fibrosis, complications resulting from diabetes, such as nephropathy, vasculopathy and neuropathy, diseases of the coronary vessels, restenosis following angioplasty, raised intra-ocular pressure, glaucoma, abnormal vascular growth, hyperaldosteronism, cognitive impairment, alzheimers, dementia, anxiety states and cognitive disorders.
Reactivity of Neopentyl-Like Compounds in the Synthesis of Branched Polyethers
Dale, Johannes,Fredriksen, Siw B.
, p. 278 - 282 (2007/10/02)
Two singly branched symmetrical hexaethers have been synthesized, starting from 2-bromomethyl-2-methyl-1,3-dibromopropane, in a surprisingly efficient one-pot nucleophilic substitution reaction.It is proposed that the expected adverse neopentyl effect is compensated by favourable neighbouring-group participation involving a 'bromonium'-like four-membered-ring transition state.The corresponding trichloride also reacted cleanly, although much more slowly, while the tritosylate gave an oxetane derivative.
