54657-09-9 Usage
Uses
Used in Pharmaceutical Industry:
TRANS-CYCLOHEXANE-1,4-DICARBOXYLIC ACID DIAMIDE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its ability to form stable complexes with metal ions makes it useful in catalysis and other chemical processes in the development of new drugs.
Used in Agrochemical Industry:
TRANS-CYCLOHEXANE-1,4-DICARBOXYLIC ACID DIAMIDE is used as a chemical intermediate in the synthesis of agrochemicals. Its potential applications in agriculture can contribute to the development of new and improved pesticides and other agrochemical products.
Used in Polymer and Plastics Production:
TRANS-CYCLOHEXANE-1,4-DICARBOXYLIC ACID DIAMIDE is used as an important intermediate in the production of certain polymers and plastics. Its versatility in forming stable complexes with metal ions can contribute to the development of new materials with enhanced properties.
Used in Research Applications:
TRANS-CYCLOHEXANE-1,4-DICARBOXYLIC ACID DIAMIDE has a wide range of potential uses in various research applications. Its ability to form stable complexes with metal ions can be utilized in the development of new catalysts, chemical processes, and other innovative technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 54657-09-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,6,5 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 54657-09:
(7*5)+(6*4)+(5*6)+(4*5)+(3*7)+(2*0)+(1*9)=139
139 % 10 = 9
So 54657-09-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H14N2O2/c9-7(11)5-1-2-6(4-3-5)8(10)12/h5-6H,1-4H2,(H2,9,11)(H2,10,12)
54657-09-9Relevant academic research and scientific papers
Synthesis and mesomorphic properties of trans-[1,4-bis5-R-pyrimidin-2-yl]-cyclohexanes and 1,2-bis-(5-R-pyrimidin-2-yl)ethanes
Mikhaleva,Kuznetsova
, p. 310 - 315 (2007/10/03)
New trans-bis(5-R-pyrimidin-2-yl)-1,4-cyclohexanes and -1,2-ethanes (R = C7H15, C6H4OR1, where R1 = H, COCH3, C4H9, C5H11, C8/su
Synthesis of analogues of N (2 chloroethyl) N' trans 4 methylcyclohexyl) N nitrosourea for evaluation as anticancer agents
Johnston,McCaleb,Clayton,Frye,Krauth,Montgomery
, p. 279 - 290 (2007/10/04)
The superior activity of N (2 chloroethyl) N' (trans 4 methylcyclohexyl) N nitrosourea (MeCCNU) against advanced murine Lewis lung carcinoma in comparisons with the cis form and other nitrosoureas prompted the synthesis of a number of MeCCNU analogues, including several cis trans pairs. The methyl group was replaced by a variety of substituents (CO2H, CH2CO2H, CO2Me, CH2OAc, CH2Cl, OMe); the trans 3 methylcyclohexyl, cis 2 methyl 1,3 dithian 5 yl, cis and trans 2 methyl 1,3 dithian 5 yl tetraoxide, and 1 methylhexyl (open chain) analogues were also prepared. Preliminary tests against murine leukemia L1210 revealed therapeutic indices (ED50/LD10) ranging from 0.26 to 0.79; all but 3 analogues effected 50% cure rates at nontoxic doses, the open chain analogue being one of the least active. In terms of therapeutic index, diequatorial (trans 4) isomers were, with one exception, as active as or, in 4 of the 8 examples, somewhat more active than the corresponding axial equatorial (cis 4) isomers. In this series, 4 of the 5 2-fluoroethyl analogues prepared were clearly inferior to the corresponding 2 chloroethyl analogues.
