70925-16-5 Usage
Uses
Used in High-Performance Polymers Industry:
cis-Cyclohexane-dicarboxylic acid-(1,4)-diamide is used as a building block for the polymerization of high-performance polymers such as polycyclohexylether (PCHE) and polyetherimide (PEI). These polymers are valued for their exceptional thermal and chemical resistance, making them suitable for various engineering applications.
Used in Adhesives, Coatings, and Sealants Industry:
cis-Cyclohexane-dicarboxylic acid-(1,4)-diamide is also utilized in the production of adhesives, coatings, sealants, and other industrial products. Its properties contribute to the enhanced performance and durability of these products in various applications.
Safety Precautions:
It is crucial to handle cis-CHDA with care, as it can cause eye and skin irritation. Additionally, it may have harmful effects if ingested or inhaled, necessitating proper safety measures during its use and storage.
Check Digit Verification of cas no
The CAS Registry Mumber 70925-16-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,9,2 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 70925-16:
(7*7)+(6*0)+(5*9)+(4*2)+(3*5)+(2*1)+(1*6)=125
125 % 10 = 5
So 70925-16-5 is a valid CAS Registry Number.
70925-16-5Relevant academic research and scientific papers
Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats
Bengtsson, Christoffer,Blaho, Stefan,Saitton, David Blomberg,Brickmann, Kay,Broddefalk, Johan,Davidsson, ?jvind,Drmota, Tomas,Folmer, Rutger,Hallberg, Kenth,Hallén, Stefan,Hovland, Ragnar,Isin, Emre,Johannesson, Petra,Kull, Bengt,Larsson, Lars-Olof,L?fgren, Lars,Nilsson, Kristina E.,Noeske, Tobias,Oakes, Nick,Plowright, Alleyn T.,Schnecke, Volker,Sthlberg, Pernilla,S?rme, Pernilla,Wan, Hong,Wellner, Eric,?ster, Linda
, p. 3039 - 3053 (2011/06/27)
Inhibition of acetyl-CoA carboxylases has the potential for modulating long chain fatty acid biosynthesis and mitochondrial fatty acid oxidation. Hybridization of weak inhibitors of ACC2 provided a novel, moderately potent but lipophilic series. Optimization led to compounds 33 and 37, which exhibit potent inhibition of human ACC2, 10-fold selectivity over inhibition of human ACC1, good physical and in vitro ADME properties and good bioavailability. X-ray crystallography has shown this series binding in the CT-domain of ACC2 and revealed two key hydrogen bonding interactions. Both 33 and 37 lower levels of hepatic malonyl-CoA in vivo in obese Zucker rats.
