54669-75-9

Upstream product

• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 637-69-4 4-Methoxystyrene 
• 108-94-1 cyclohexanone 
• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 80676-78-4 tert-butyl((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane 
• 137604-04-7 1-(Cyclohex-1-enesulfinyl)-4-methyl-benzene 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 54670-26-7 2-hydroxy-5-[2-(4-methoxy-phenyl)-4,5,6,7-tetrahydro-indol-1-yl]-benzoic acid 
• 62368-44-9 1-(2-dimethylaminoethyl)-2(p-methoxyphenyl)-4,5,6,7-tetrahydroindole 
• 1450892-99-5 1-benzyl-2-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-indole 
• 5784-95-2 2-(4-methoxyphenyl)-1H-indole 
• 120110-28-3 2-p-methoxyphenyl-4,5,6,7-tetrahydrothiophene 

Relevant academic research and scientific papers

Synthesis of Substituted Anilines from Cyclohexanones Using Pd/C-Ethylene System and Its Application to Indole Synthesis

The synthesis of anilines and indoles from cyclohexanones using a Pd/C-ethylene system is reported. A simple combination of NH4OAc and K2CO3 under nonaerobic conditions was found to be the most suitable to perform this reaction. Hydrogen transfer between cyclohexanone and ethylene generates the desired products. The reaction tolerates a variety of substitutions on the starting cyclohexanones.

Gold(I)-Catalyzed Synthesis of Highly Substituted 1,4-Dicarbonyl Derivatives via Sulfonium [3,3]-Sigmatropic Rearrangement

An efficient and straightforward gold-catalyzed protocol for the synthesis of 2-substituted 4-oxo-4-arylbutanal derivatives from commercially available or easily accessible alkynes and vinylsulfoxide substrates has been developed. Extension of the methodology to the use of 1-cycloalkenyl sulfoxides allowed the facile synthesis of five-, six-, and seven-membered-ring cycloalkyl-1-one backbone. Subsequently, the tetrahydrocycloalkyl[b]pyrrole derivatives, which are found in many active pharmaceutical ingredients, were isolated in good yields. Mechanistic investigation highlighted a [3,3]-sigmatropic rearrangement of a sulfonium intermediate in this process.

Sunlight-driven synthesis of γ-diketones via oxidative coupling of enamines with silyl enol ethers catalyzed by [Ru(bpy)3]2+

A photosensitizer [Ru(bpy)3]2+ catalyzes oxidative coupling reaction of enamines with silyl enol ethers under visible light irradiation by a Xe lamp or sunlight to produce γ-diketones. A 2e-oxidation process involved in this reaction

The cascade carbo-carbonylation of unactivated alkenes catalyzed by an organocatalyst and a transition metal catalyst: A facile approach to γ-diketones and γ-carbonyl aldehydes from arylalkenes under air

A novel cascade carbo-carbonylation reaction of unactivated arylalkenes with ketones or aldehydes was catalyzed by an organocatalyst and a transition metal catalyst via a SOMO-enamine under air, affording a simple approach to γ-diketones and γ-carbonyl aldehydes. The Royal Society of Chemistry 2010.

Substituted N-aminoalkylpyrroles

Substituted N-aminoalkylpyrroles of the formula: STR1 IN WHICH X, Z, R1, -R5 and n are as defined below, and their physiologically tolerable acid addition salts are disclosed to have antiarrhythmic, central nervous system depressant,

Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent

Novel N-phenylpyrroles are disclosed that are effective in the treatment of inflammation and pain in mammals and have the formula SPC1 Wherein R is hydrogen, alkyl of one to six carbon atoms, thienyl, phenyl or phenyl substituted by halogen, trifluorometh