80676-78-4

Basic information

• Product Name: tert-butyl((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane
• Synonyms: tert-butyl((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane
• CAS NO: 80676-78-4
• Molecular Weight: 264.44
• Mol File: 80676-78-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: tert-butyl((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane(80676-78-4)
• EPA Substance Registry System: tert-butyl((1-(4-methoxyphenyl)vinyl)oxy)dimethylsilane(80676-78-4)

Safety Data

• Hazardous Substances Data: 80676-78-4(Hazardous Substances Data)

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 77086-38-5 ketene t-butyldimethylsilyl methyl acetal 

Downstream Products

• 1151770-63-6 (1S,2R)-methyl 1-(4-bromophenyl)-2-(tert-butyldimethylsilyloxy)-2-(4-methoxyphenyl)cyclopropanecarboxylate 
• 1151770-64-7 (1S,2S)-methyl 1-(4-bromophenyl)-2-(tert-butyldimethylsilyloxy)-2-(4-methoxyphenyl)cyclopropanecarboxylate 
• 90720-38-0 3-(tert-Butyl-dimethyl-silanyloxy)-4-ethyl-1-(4-methoxy-phenyl)-hex-3-en-1-one 
• 90720-29-9 3-(tert-Butyl-dimethyl-silanyloxy)-2,2-diethyl-3-(4-methoxy-phenyl)-cyclobutanone 
• 90720-43-7 4-Ethyl-1-(4-methoxy-phenyl)-hexane-1,3-dione 
• 41501-69-3 3,3-dichloro-1-(4-methoxyphenyl)-2-propen-1-one 
• 55234-56-5 4-(4-methoxy-phenyl)-4-oxo-butyronitrile 

Relevant articles and documents

FLP-Catalyzed Transfer Hydrogenation of Silyl Enol Ethers

Herein we report the first catalytic transfer hydrogenation of silyl enol ethers. This metal free approach employs tris(pentafluorophenyl)borane and 2,2,6,6-tetramethylpiperidine (TMP) as a commercially available FLP catalyst system and naturally occurring γ-terpinene as a dihydrogen surrogate. A variety of silyl enol ethers undergo efficient hydrogenation, with the reduced products isolated in excellent yields (29 examples, 82 % average yield).

The synthesis of pyrroles and oxazoles based on gold α-imino carbene complexes

Cationic gold complexes of α-oximimino carbenes have been identified to react with weak nucleophiles including enol ethers and nitriles. These findings allowed us to develop the highly efficient synthesis of pyrroles and oxazoles.

[4+2]-Annulations of aminocyclobutanes

The first [4 + 2]-annulation between aminocyclobutanes and aldehydes to access tetrahydropyranyl amines is reported. With phthalimido cyclobutane dicarboxylates and aromatic aldehydes, tetrahydropyrans were obtained in 53-92% yield and 3:1-17:1 dr using scandium triflate or iron trichloride as catalyst. The use of thymine-or fluorouracil-substituted cyclobutanes gave direct access to six-membered ring nucleoside analogues. Finally, the [4 + 2]-annulation between aminocyclobutanes and enol ethers led to the corresponding cyclohexylamines.