54672-55-8

Basic information

• Product Name: 2,3-dihydro-1H-indene-2-carbonyl chloride
• Synonyms: 2,3-dihydro-1H-indene-2-carbonyl chloride
• CAS NO: 54672-55-8
• Molecular Formula: C₁₀H₉ClO
• Molecular Weight: 180.63086
• Mol File: 54672-55-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-dihydro-1H-indene-2-carbonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-1H-indene-2-carbonyl chloride(54672-55-8)
• EPA Substance Registry System: 2,3-dihydro-1H-indene-2-carbonyl chloride(54672-55-8)

Safety Data

• Hazardous Substances Data: 54672-55-8(Hazardous Substances Data)

Upstream product

• 25177-85-9 2-indancarboxylic acid 

Downstream Products

• 175079-50-2 2-Carbamoylindane 
• 608534-44-7 2-(2,3-dihydro-1H-inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 939-23-1 p-phenylpyridine 
• 1210069-29-6 C₂₂H₂₄N₂O₅ 
• 33982-86-4 (2,3-dihydro-1H-inden-2-yl)(phenyl)methanone 
• 53273-37-3 indan-2-yl-acetic acid methyl ester 

Relevant articles and documents

Palladium-Catalyzed Migratory Insertion of Carbenes and C-C Cleavage of Cycloalkanecarboxamides

A palladium catalyzed reaction of cycloalkanecarboxamides and diazomalonates or bis(phenylsulfonyl)diazomethane has been developed. The reaction proceeds via carbene migratory insertion and cascade C-C cleavage pathways. Cycloalkanecarboxamides with four to seven membered rings are applicable in the transformation. A series of ring opening products were prepared with moderate yields. The finding provides valuable clues for the development of new reactions involving carbene migratory insertion and the cleavage of unstrained C(sp3)-C(sp3) bonds.

Copper-Catalyzed Oxidative Benzylic C(sp3)?H Cyclization for the Synthesis of β-Lactams

β-Lactams are important structural motifs because of their ubiquity in natural products and pharmaceuticals. We report herein a Cu-catalyzed intramolecular oxidative C(sp3)?H amidation for the synthesis of β-lactams using tBuOOtBu. This method

NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF

PROBLEM TO BE SOLVED: To provide a nitrogen-containing heterocyclic amide compound having pyruvate dehydrogenase kinase inhibitory activity, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same. SOLUTION: The present invention provides a compound of formula [I-a] or formula [II], or a pharmaceutically acceptable salt thereof (a bond of a dotted line: a single bond or a double bond. X1: C, N, O. X2: C, N. R1a: C1-4 alkyl, C1-4 alkyl carbonyl. R2: halogen, cyano, C1-4 alkyl. A1-A7: C, N, O. A8: C, N. R3, R4: H, C1-4 alkyl. Cy1: C4-6 cycloalkyl or the like. Cy2: C3-6 cycloalkyl or the like. m, t, w: 0, 1. n, r, v: 0, 1, 2.) SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT