5468-12-2Relevant academic research and scientific papers
Recyclable fluorous organocatalysts promoted three-component reactions of pyruvate, aldehyde and amine at room temperature
Qian, Jin-Long,Yi, Wen-Bin,Cai, Chun
supporting information, p. 7100 - 7102 (2013/12/04)
A new fluorous imine carbothioate has been prepared as an organocatalyst for the synthesis of pyrrol-2-ones via the cyclo-condensation reaction of aldehydes, amines, and pyruvate at room temperature. The fluorous catalyst can be easily recovered from the reaction mixture by simple fluorous solid-phase extraction (F-SPE) and used for next run reaction without further purification.
Organocatalytic three-component reactions of pyruvate, aldehyde and aniline by hydrogen-bonding catalysts
Li, Xin,Deng, Hui,Luo, Sanzhong,Cheng, Jin-Pei
experimental part, p. 4350 - 4356 (2009/04/11)
Hydrogen-bonding catalysts have been found to catalyze one-pot three-component reactions of pyruvate, anilines and aldehydes to afford versatile 3-amino-1,5-dihydro-2H-pyrrol-2-ones in high yields. Both, thioureas and phosphoric acids are viable catalysts
FIVE-MEMBERED 2,3-DIOXOHETEROCYCLES. I. SYNTHESIS AND STRUCTURE OF 1,5-DIARYLTETRAHYDRO-2,3-PYRROLEDIONES
Andreichikov, Yu. S.,Gein, V. L.,Ivanenko, O. I.,Maslivets A. N.
, p. 1983 - 1988 (2007/10/02)
Ethyl pyruvate reacts with Schiff bases to form 1,5-diaryl-3-arylamino-2,5-dihydro-2-pyrrolones, which are hydrolyzed by concentrated hydrochloric acid to 1,5-diaryltetrahydro-2,3-pyrrolediones.Pyrrolediones containing electron-donating substituents in th
