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Usage

Uses

Used in Pharmaceutical Industry:
(4Z)-4-[(4-iodophenyl)amino]methylidene-N-(2-methoxyphenyl)-3-oxo-3,4-dihydronaphthalene-2-carboxamide is used as a potential pharmaceutical compound for its unique molecular structure that may exhibit specific biological activities. The presence of the naphthalene core, amine, methoxy group, carboxamide group, 4-iodophenyl group, and methylidene group could provide the compound with properties that make it suitable for targeting various biological pathways or receptors.
Used in Chemical Research:
In the field of chemical research, (4Z)-4-[(4-iodophenyl)amino]methylidene-N-(2-methoxyphenyl)-3-oxo-3,4-dihydronaphthalene-2-carboxamide can be used as a subject for studying the effects of its structural elements on its chemical and biological properties. This may lead to the development of new compounds with improved or novel applications in various industries, including pharmaceuticals, materials science, and more.
Used in Drug Design and Development:
(4Z)-4-[(4-iodophenyl)amino]methylidene-N-(2-methoxyphenyl)-3-oxo-3,4-dihydronaphthalene-2-carboxamide's unique structure may also make it a candidate for drug design and development, particularly in the search for new therapeutic agents. Its potential use in this application is based on the possibility that its molecular components could interact with specific biological targets, such as enzymes, receptors, or other proteins, to elicit a desired therapeutic effect.

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Relevant academic research and scientific papers

Poly(2-oxazoline) hydrogels crosslinked with aliphatic bis(2-oxazoline)s: Properties, cytotoxicity, and cell cultivation

A series of hydrogels from 2-ethyl-2-oxazoline and three bis(2-oxazoline) crosslinkers - 1,4-butylene-2,2′-bis(2-oxazoline), 1,6-hexamethylene-2,2′-bis(2-oxazoline), and 1,8-octamethylene-2,2′-bis(2-oxazoline) - are prepared. The hydrogels differ by the length of aliphatic chain of crosslinker and by the percentage of crosslinker (2-10%). The influence of the type and the percentage of the crosslinker on swelling properties, mechanical properties, and state of water is studied. The equilibrium swelling degree in water ranges from 2 to 20. With a proper selection of the crosslinker, Young's modulus can be varied from 10 kPa to almost 100 kPa. To evaluate the potential for medical applications, the cytotoxicity of extracts and the contact toxicity toward murine fibroblasts are measured. The hydrogels with the crosslinker containing a shorter aliphatic exhibit low toxicity toward fibroblast cells. Moreover, the viability and the proliferation of pancreatic β-cells incubated inside hydrogels for 12 days are analyzed.