54714-44-2

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 5333-34-6 3-(3,4-dimethoxybenzoyl)propionic acid 
• 13575-75-2 6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydronaphthalene 

Downstream Products

• 57595-88-7 allyl-(7,8-dimethoxy-4,5-dihydro-naphtho[1,2-d]thiazol-2-yl)-amine 
• 57595-89-8 7,8-dimethoxy-2-methyl-4,5-dihydro-naphtho[1,2-d]thiazole 
• 57595-86-5 7,8-dimethoxy-4,5-dihydro-naphtho[1,2-d]thiazol-2-ylamine 
• 1354964-51-4 (E)-2-(2-(7,8-dimethoxy-4,5-dihydronaphtho[1,2-d]thiazol-2-yl)hydrazono)-3-(2-nitrophenyl)propanoic acid 
• 1354964-52-5 (Z)-2-(2-(7,8-dimethoxy-4,5-dihydronaphtho[1,2-d]thiazol-2-yl)hydrazono)-3-(2-nitrophenyl) propanoic acid 
• 1021529-09-8 C₂₃H₂₈N₂O₃ 
• 57595-87-6 (7,8-dimethoxy-4,5-dihydro-naphtho[1,2-d]thiazol-2-yl)-phenyl-amine 

Relevant academic research and scientific papers

COMPOUNDS FOR THE INHIBITION OF CELLULAR PROLIFERATION

Compositions and methods for inhibiting translation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, (4) disorders associated with viral infections, and/or (5) non-proliferative metabolic disorders such as type II diabetes where inhibition of translation initiation is beneficial using the compounds disclosed herein.

2-Aminotetralones: Novel inhibitors of MurA and MurZ

Several 2-aminotetralones were identified as novel inhibitors of the bacterial enzymes MurA and MurZ. A number of these inhibitors demonstrated antibacterial activity against Staphylococcus aureus and Escherichia coli with MICs in the range 8-128 μg/ml. B

Facile transformation of 1-methoxynaphthalenes to octahydrophenanthrenes. Application to the total synthesis of (±)-sempervirol methyl ether, (±)-sugiol methyl ether, (±)-nimbiol methyl ether, and (±)-nimbidiol dimethyl ether

An efficient general method has been developed for the synthesis of the tricyclic aromatic ketones 4, 12, 13 and 14 from the 1-methoxynaphthalenes 8, 9, 10 and 11 respectively. The transformations of the ketones 4, 12, 13 and 14 into the diterpene ethers (±)-sempervirol methyl ether (7), (±)-sugiol methyl ether (15), (±)-nimbiol methyl ether (16), and (±)-nimbidiol dimethyl ether (17) have been successfully accomplished involving reductive methylation in liquid ammonia as the key reaction.

Substituted naphtho pyrazoles

Substituted naphtho [1,2-c] pyrazoles, e.g., 3-(4-pyridyl)-2H-naphtho[1,2-c]-pyrazole, are useful as non-estrogenic anti-fertility agents.

Substituted indeno, naphtho and cyclohepta pyrazoles

Substituted indeno [1,2-c] pyrazoles, naphtho [1,2-c] pyrazoles and benzo [6,7] cyclohepta [1,2-c] pyrazoles e.g., 3-(2,3-dimethoxyphenyl)-4H-indeno[1,2-c] pyrazole and 4,5-dihydro-3-(4-pyridyl)-2H-naphtho[1,2-c] pyrazole, are useful as non-estrogenic anti-fertility agents and antihypertensive agents.