13575-75-2

Basic information

• Product Name: 6,7-Dimethoxy-1-tetralone
• Synonyms: 6,7-DIMETHOXY-1-TETRALONE;6,7-DIMETHOXY-1-TETRALONE, 97%%;6,7-Dimethoxy-3,4-dihydro-2H-naphthalen-1-one;6,7-dimethoxytetralin-1-one;4-dihydro-6;7-diMethoxy-;6,7-diMethoxy-3,4-dihydronaphthalen-1(2H)-one;6,7-Dimethoxy-1-tetralone 97%
• CAS NO: 13575-75-2
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.24
• Product Categories: C11 to C12;Carbonyl Compounds;Ketones
• Mol File: 13575-75-2.mol
• Article Data: 27

Chemical Properties

• Melting Point: 98-100 °C(lit.)
• Boiling Point: 358.3°Cat760mmHg
• Flash Point: 161.8°C
• Appearance: White to off-white/Crystalline Powder or Crystals
• Density: 1.14g/cm³
• Vapor Pressure: 0.0402mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 6,7-Dimethoxy-1-tetralone(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-Dimethoxy-1-tetralone(13575-75-2)
• EPA Substance Registry System: 6,7-Dimethoxy-1-tetralone(13575-75-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 13575-75-2(Hazardous Substances Data)

Usage

Uses

6,7-Dimethoxy-1-tetralone was used in the synthesis of 2-bromotetralones by undergoing bromination. It was also used as a precursor to quinolines with dopaminergic activity, naphthols with anti-inflammatory activity and benzophenanthridine alkaloids with antitumor activity.

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 2939, 1983 DOI: 10.1016/S0040-4039(00)88063-6

General Description

6,7-Dimethoxy-1-tetralone reacts with 2-amino-4,5-dimethoxyacetophenone to form 5,6-dihydro-2,3,9,10-tetramethoxybenz[c]acridine.

InChI:InChI=1/C8H6BrFO/c9-5-8(11)6-3-1-2-4-7(6)10/h1-4H,5H2

Upstream product

• 13575-74-1 4-(3,4-dimethoxyphenyl)butanoic acid 
• 5333-34-6 3-(3,4-dimethoxybenzoyl)propionic acid 
• 348143-75-9 4-(3,4-dimethoxyphenyl)butanoic acid chloride 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 5703-21-9 3,4-dimethoxyphenylacetaldehyde 
• 231935-01-6 ethyl 4-(3,4-dimethoxyphenyl)butanoate 
• 35491-95-3 6,7-dimethoxy-1-hydroxytetraline 
• 137744-82-2 C₁₂H₁₄O₄ 
• 1445852-57-2 dimethyl 2-((4-(3,4-dimethoxyphenyl)butanoyl)oxy)succinate 
• 1178964-08-3 6',7'-dimethoxy-3',4'-dihydro-2'H-spiro[1,3]dithiane-2,1'-naphthalene 
• 2107-70-2 3,4-methoxycinnamic acid 
• 3945-85-5 1-bromo-3-(3,4-dimethoxyphenyl)propane 
• 3929-47-3 3-(3,4-dimethoxyphenyl)-1-propanol 
• 2316-26-9 3,4-dimethoxycinnamic acid 

Downstream Products

• 65503-06-2 2-(4-benzhydryl-piperazin-1-ylmethyl)-6,7-dimethoxy-3,4-dihydro-2H-naphthalen-1-one 
• 78238-92-3 6,7-dimethoxy-1-phenyl-3,4-dihydronaphthalene 
• 78238-93-4 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-1-ol 
• 65332-34-5 N-(3,4-dihydro-6,7-dimethoxy-1-naphthyl)-2-methoxy-N-methylbenzamide 
• 54714-44-2 2-bromo-6,7-dimethoxy-1-tetralone 
• 15288-02-5 6-hydroxy-7-methoxy-1-tetralone 
• 15288-01-4 7-hydroxy-6-methoxy-3,4-dihydronaphthalen-1(2H)-one 
• 54549-75-6 6,7-dihydroxy-3,4-dihydro-1(2H)-naphthalenone 
• 17173-25-0 2-hydroxy-6,7-dimethoxynaphthalene-1,4-dione 
• 204842-93-3 5,6-dihydro-2,3,9,10-tetramethoxy-7-methylbenz[c]acridine 
• 119034-87-6 6,7-bis(benzyloxy)-3,4-dihydronaphthalen-1(2H)-one 
• 207279-90-1 6,7-Bis-benzyloxy-2,3-dihydro-[1,4]naphthoquinone 
• 52259-72-0 norfagaronine 
• 15462-10-9 2,3,8,9-tetramethoxybenzophenanthridine 

Relevant articles and documents

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