5472-06-0 Usage
General Description
2-Butylamino-2-phenylacetic acid is a chemical compound with the molecular formula C12H17NO2. It is a derivative of phenylacetic acid and contains a butylamino group. 2-butylamino-2-phenyl-acetic acid is primarily used as a pharmaceutical intermediate in the synthesis of various drugs, including anti-inflammatory and analgesic agents. Its structure and properties make it suitable for modification and incorporation into various drug molecules to enhance their biological activity and reduce potential side effects. The compound's pharmacological properties and potential medical applications contribute to its importance in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 5472-06-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,7 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5472-06:
(6*5)+(5*4)+(4*7)+(3*2)+(2*0)+(1*6)=90
90 % 10 = 0
So 5472-06-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H17NO2/c1-2-3-9-13-11(12(14)15)10-7-5-4-6-8-10/h4-8,11,13H,2-3,9H2,1H3,(H,14,15)
5472-06-0Relevant articles and documents
Diastereoselective Petasis Mannich reactions accelerated by hexafluoroisopropanol: A pyrrolidine-derived arylglycine synthesis
Nanda, Kausik K.,Trotter, B. Wesley
, p. 2025 - 2028 (2005)
A diastereoselective synthesis of pyrrolidine-derived arylglycines has been developed using the Petasis boronic acid Mannich reaction. High diastereoselectivities in the reactions of chiral amines, aryl boronic acids, and glyoxylic acid monohydrate have been demonstrated for the first time. Key to the implementation of this method is the discovery that hexafluoroisopropanol accelerates the Petasis process, reducing reaction times from multiple days to less than 24 h.