5472-32-2

Basic information

• Product Name: 1,2-bis(4-bromophenyl)-1,2-diphenylethane-1,2-diol
• CAS NO: 5472-32-2
• Molecular Formula: C₂₆H₂₀Br₂O₂
• Molecular Weight: 524.2438
• Mol File: 5472-32-2.mol

Chemical Properties

• Boiling Point: 591.9°C at 760 mmHg
• Flash Point: 311.8°C
• Density: 1.549g/cm³
• Vapor Pressure: 7.42E-15mmHg at 25°C
• Refractive Index: 1.672
• CAS DataBase Reference: 1,2-bis(4-bromophenyl)-1,2-diphenylethane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(4-bromophenyl)-1,2-diphenylethane-1,2-diol(5472-32-2)
• EPA Substance Registry System: 1,2-bis(4-bromophenyl)-1,2-diphenylethane-1,2-diol(5472-32-2)

Safety Data

• Hazardous Substances Data: 5472-32-2(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 28 carbon (C) atoms, 22 hydrogen (H) atoms, 2 bromine (Br) atoms, and 2 oxygen (O) atoms.

Explanation

This describes the arrangement of atoms and functional groups in the molecule. It consists of two phenyl rings (C6H5), each with a bromine substituent (Br) at the 4th position, attached to a carbon chain (ethane) with two phenyl groups (C6H5) and two hydroxyl groups (OH) at the 1,2 positions.

Explanation

The compound is classified as an organic compound because it contains carbon and hydrogen atoms, along with other elements like bromine and oxygen.

Explanation

The compound has two bromine atoms attached to the phenyl rings at the 4th position, which can influence its chemical reactivity and properties.

Explanation

The molecule contains four phenyl rings in total, two of which are part of the 1,2-bis(4-bromophenyl) group, and the other two are attached to the ethane chain.

Explanation

The compound has two hydroxyl (OH) groups, which give it diol functionality. This can lead to hydrogen bonding and affect the compound's solubility and reactivity.

Explanation

Due to its unique structure and functional groups, the compound can be used as a starting material or intermediate in the synthesis of more complex organic molecules.

Explanation

The compound is of interest in the field of pharmaceutical research and medicinal chemistry due to its potential biological activity, which could lead to the development of new drugs or therapeutic agents.

Explanation

The compound's unique structure and functional groups may allow it to interact with biological targets, such as enzymes or receptors, which could result in potential therapeutic effects.

Explanation

The solubility of the compound in various solvents is not provided in the material. However, the presence of hydroxyl groups may suggest some level of solubility in polar solvents like water or alcohols.

Chemical structure

1,2-bis(4-bromophenyl)-1,2-diphenylethane-1,2-diol

Organic compound

Yes

Bromine substituents

Two

Phenyl rings

Four

Hydroxyl groups

Two

Building block in organic synthesis

Yes

Pharmaceutical research and medicinal chemistry

Interest

Potential biological activity

Yes

Solubility

Not specified

Upstream product

• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 18620-02-5 (4-bromophenyl)magnesium bromide 
• 134-81-6 benzil 
• 60-29-7 diethyl ether 
• 71-43-2 benzene 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 

Downstream Products

• 29334-16-5 phenyl(4-bromophenyl)methanol 
• 90-90-4 (4-bromophenyl)(phenyl)methanone 
• 176955-47-8 9,10-bis-(4-bromophenyl)phenanthrene 

Relevant articles and documents

Preparation of Condensed Aromatics by Superacidic Dehydrative Cyclization of Arvl Pinacols and Eooxides

Aryl pinacols and epoxides, respectively, are cleanly and in high yield converted via superacidic dehydrative cyclization to the corresponding condensed aromatics. Dehydrative cyclization of benzopinacol (1a), triphenylacetophenone (2), and tetraphenylethylene oxide (9) give 9,10-diphenylphenanthrene (3a) as the major product in acidic media stronger than Ho = -11. Aryl pinacol 12a forms the condensed aromatic 13a as the major product in acidic media stronger than Ho = -13.5. It is proposed that the dehydrative cyclizations to provide aromatics 3a and 13a occurs through dicationic intermediates. Substituted benzopinacols 1f, 1g, and 1j are prepared and give the corresponding phenanthrenes (3f, 3g, and 3j) in high yields. The regiochemistry of the cyclization of substituted benzopinacols is controlled by deactivating substituents on the aryl rings. Aryl pinacols (12a-d) derived from acenaphthenequinone and pinacol 15 also give condensed aromatics (13a-d and 16, repectively) with superacidic triflic acid.

The preparation of substituted phenanthrenes from aryl pinacols in superacid

Reactions of aryl pinacols with the superacidic triflic acid give rise to substituted phenanthrenes in good yields.

Cp2TiCl2-CATALYZED REACTION OF GRIGNARD REAGENTS WITH DIARYL KETONES, FORMATION OF PINACOLIC COUPLING FROM DIARYL KETONES

Diaryl ketones react with Grignard reagents in the presence of a catalytic amount of Cp2TiCl2 to give the corresponding pinacolic coupling products.