54723-13-6Relevant academic research and scientific papers
Gold(i)-catalyzed formation of dihydroquinolines and indoles from N-aminophenyl propargyl malonates
Gronnier, Colombe,Odabachian, Yann,Gagosz, Fabien
supporting information; experimental part, p. 218 - 220 (2011/03/19)
The use of [XPhosAu(NCMe)]SbF6 in nitromethane at 100 °C allows the rapid and efficient formation of variously substituted dihydroquinolines, which can be subsequently converted into indoles by a rare photochemical rearrangement.
Conjugated imines and iminium salts as versatile acceptors of nucleophiles
Shimizu, Makoto,Hachiya, Iwao,Mizota, Isao
scheme or table, p. 874 - 889 (2009/07/10)
Growing interests in nitrogen-containing molecules involving bioactive and functional materials have stimulated the recent development of synthetic methodologies where nucleophilic addition reactions to imino carbons are utilized in crucial steps. This article summarizes double nucleophilic addition reactions with α,β-unsaturated aldimines, addition reactions using alkynyl imines, "umpoled" reactions of α-imino esters, and the use of iminium salts as reactive electrophiles. The Royal Society of Chemistry 2009.
Oxaziridine-mediated amination of primary amines: Scope and application to a one-pot pyrazole synthesis
Armstrong, Alan,Jones, Lyn H.,Knight, Jamie D.,Kelsey, Richard D.
, p. 713 - 716 (2007/10/03)
(Chemical Equation Presented) Electrophilic amination of primary aliphatic and aromatic amines is reported using a diethylketomalonate-derived oxaziridine to afford the corresponding N-Boc hydrazines in good to excellent yields. The method allows a one-pot synthesis of pyrazoles from primary amines.
Electrophilic amination with iminomalonate
Niwa, Yasuki,Takayama, Kazuki,Shimizu, Makoto
, p. 5473 - 5476 (2007/10/03)
Diethyl N-anisyliminomalonate has been found to be an excellent electrophilic amination reagent for Grignard reagents to give N-alkylated products in good yields, and subsequent air oxidation affords N-alkylanisidines.
Environmentally benign chemistry: Microwave-induced stereocontrolled synthesis of β-lactam synthons
Banik, Bimal K.,Manhas, Maghar S.,Robb, Ernest W.,Bose, Ajay K.
, p. 405 - 415 (2007/10/03)
Microwave irradiation in open glass vessels in unmodified commercial microwave ovens has permitted stereocontrolled synthesis of useful β-lactam synthons not withstanding the fact that the nature of specific activation (if any) of organic reactions by mic
