54729-18-9Relevant academic research and scientific papers
1,2,4-triazole derivative containing chlorobenzopyrazine structure and preparation method and application thereof
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, (2017/08/27)
The invention discloses a 1,2,4-triazole derivative containing a chlorobenzopyrazine structure and a preparation method and an application thereof. The 1,2,4-triazole derivative is prepared by the steps: adopting 4-chloro-2-nitroaniline and hydrazine hydrate to generate a compound (II); then carrying out a reaction of the compound (II) with MBF, to obtain a product (III); chloridizing the compound (III) with POCl3 to obtain a product (IV); carrying out a reaction of the compound (IV) and hydrazine hydrate to obtain an intermediate product (V); and carrying out a reaction of the compound (V) with a substituted acid compound with POCl3 as a solvent, to obtain the 1,2,4-triazole derivative containing the chlorobenzopyrazine structure and represented by the formula (I). The raw materials are simple and easily available, the preparation method is simple, the postprocessing is convenient, the product yield is high, and the compound has weeding activity, has good weeding effect on bentgrass and lettuce weeds, and provides the foundation for research and development of new pesticides.
Application of 1,2,4-triazole derivatives containing chlorobenzopyrazine structure as bactericide
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, (2017/06/08)
The invention discloses an application of 1,2,4-triazole derivatives containing a chlorobenzopyrazine structure as a bactericide. The derivatives are prepared by the following steps: reacting 4-chloro-ortho-nitroaniline with hydrazine hydrate to generate a compound (II), reacting the compound (II) with MBF to obtain a product (III), chlorinating the compound (III) by POCl3 to obtain a product (IV), reacting the compound (IV) with hydrazine hydrate to obtain an intermediate product (V), reacting the compound (V) with substituted acid compounds in a POCl3 solvent to obtain the 1,2,4-triazole derivatives with a chlorobenzopyrazine structure represented by the formula (I). The raw materials are easily available, the preparation method is simple, the post treatment is convenient, the product yield is high, moreover, the compounds have a bacterial killing activity, the control effect on colletotrichum acutatum, strawberry colletotrichum, and wolfberry colletotrichum is especially good, and the derivatives can be used to develop novel pesticides.
Application of hydrazone compound with chlorine-containing quinoxaline structure as bactericide
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Paragraph 0030, (2017/04/27)
The invention discloses an application of a hydrazone compound with a chlorine-containing quinoxaline structure as a bactericide. According to the application, a compound 1 is prepared from 5-chloro-o-nitroaniline and hydrazine hydrate; a compound 2 is prepared from the compound 1 and BMF; a compound 3 is prepared through subjecting the compound 2 to a reaction with phosphorus oxychloride; a compound 4 is prepared through subjecting the compound 3 to a reaction with hydrazine hydrate; and a compound (I) is prepared through subjecting the compound 4 to a reaction with a substituted aldehyde compound. According to the application, the raw materials are simple and readily-available, the preparation method is simple, the aftertreatment is convenient, and the product yield is high; and the compound has antifungal activity and particularly has a good bactericidal effect on Colletotrichum acutata, Colletotrichum fragaliae and Colletotrichum gloeosporioides, thereby providing a foundation for the research and development of novel pesticides.
Hydrazone compound containing chlorobenzopyrazine and preparation method and application thereof
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Paragraph 0014; 0015; 0027, (2017/08/25)
The invention discloses a hydrazone compound containing chlorobenzopyrazine and a preparation method and application thereof. The preparation method comprises the following steps: carrying out a reaction between 5-chloro-o-nitroaniline and hydrazine hydrate to prepare a compound 1; carrying out a reaction between the compound 1 and BMF to prepare a compound 2; carrying out a reaction between the compound 2 and phosphorus oxychloride to prepare a compound 3; carrying out a reaction between the compound 3 and hydrazine hydrate to prepare a compound 4; and carrying out a reaction between the compound 4 and a substituted aldehyde compound to prepare a compound (I). The raw materials are simple and easily available. The preparation method is simple. Postprocessing is convenient. Product yield is high. In addition, the compound has a certain herbicidal activity, especially has a certain weeding effect on Agrostis palustris and lettuce, and provides a basis for research and development of new pesticides.
