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6-Amino-1,3-dimethyl-5-(methylamino)-2,4(1H,3H)-pyrimidinedione, also known as Pyrimethamine, is a pyrimidine derivative with the molecular formula C7H11N5O2. It is a medication primarily used for the prevention and treatment of malaria.

54729-62-3

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54729-62-3 Usage

Uses

Used in Malaria Treatment:
6-Amino-1,3-dimethyl-5-(methylamino)-2,4(1H,3H)-pyrimidinedione is used as an antimalarial agent for the prevention and treatment of malaria caused by Plasmodium falciparum. It works by inhibiting the growth and reproduction of the malaria parasite in the body.
Used in Combination Therapy:
6-Amino-1,3-dimethyl-5-(methylamino)-2,4(1H,3H)-pyrimidinedione is used in combination with other antimalarial drugs to increase its effectiveness and reduce the risk of resistance.
Used in Toxoplasmosis Treatment:
6-Amino-1,3-dimethyl-5-(methylamino)-2,4(1H,3H)-pyrimidinedione is also used in the treatment of toxoplasmosis, a parasitic infection.
Used in Rheumatoid Arthritis Treatment:
6-Amino-1,3-dimethyl-5-(methylamino)-2,4(1H,3H)-pyrimidinedione serves as a second-line treatment for rheumatoid arthritis.
Used in Pharmaceutical Industry:
6-Amino-1,3-dimethyl-5-(methylamino)-2,4(1H,3H)-pyrimidinedione is used as an essential medicine by the World Health Organization and is available in various forms, including tablets and injectable solutions.

Check Digit Verification of cas no

The CAS Registry Mumber 54729-62-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,7,2 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54729-62:
(7*5)+(6*4)+(5*7)+(4*2)+(3*9)+(2*6)+(1*2)=143
143 % 10 = 3
So 54729-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H12N4O2/c1-9-4-5(8)10(2)7(13)11(3)6(4)12/h9H,8H2,1-3H3

54729-62-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-amino-1,3-dimethyl-5-(methylamino)pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 1,3-Dimethyl-4-amino-5-methylamino-uracil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54729-62-3 SDS

54729-62-3Relevant academic research and scientific papers

Preparation methods of three kinds of methyl uric acid compounds, intermediate and preparation method of the intermediate

-

, (2019/01/07)

The invention provides preparation methods of three types of compounds which can be extracted from plants such as tea trees and have the effects of resisting depression, tranquilizing and hypnosis, resisting inflammation and easing pain, reducing stress damage of the liver cells and improving the exercise ability, an intermediate and a preparation method of the intermediate. The method is simple and convenient to operate, high in safety, high in atom economy and less in three wastes, and the raw and auxiliary materials are cheap and easy to obtain, low in toxicity, safe and stable; the reaction conditions are mild, the impurities are few, and the yield is high. The product is purified by crystallization, column chromatography is avoided, the operation is simple and feasible, and the process is stable, easy to control and convenient in reaction after-treatment, and can be economically and conveniently used for industrial production.

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