547740-66-9

Basic information

• Product Name: 4(1H)-Pyrimidinone, 5,6-diamino-2-[(phenylmethyl)thio]-
• CAS NO: 547740-66-9
• Molecular Formula: C11H12N4OS
• Molecular Weight: 248.308
• Mol File: 547740-66-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4(1H)-Pyrimidinone, 5,6-diamino-2-[(phenylmethyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 5,6-diamino-2-[(phenylmethyl)thio]-(547740-66-9)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 5,6-diamino-2-[(phenylmethyl)thio]-(547740-66-9)

Safety Data

• Hazardous Substances Data: 547740-66-9(Hazardous Substances Data)

Upstream product

• 37660-23-4 6-amino-2-benzylthio-3,4-dihydropyrimidin-4-one 
• 100-39-0 benzyl bromide 
• 1004-76-8 5,6-diamino-2,3-dihydro-2-thioxo-4(1H)-pyrimidinone 
• 66604-43-1 6-amino-2-(benzylsulfanyl)-5-nitroso-4(3H)-pyrimidinone 

Downstream Products

• 51998-91-5 6-chloro-2-phenylmethylsulfanylpurine 
• 851370-49-5 2-(benzylsulfanyl)-6-chloro-9-isopropylpurine 
• 851370-50-8 6-chloro-9-isopropyl-2-phenylmethanesulfonyl-9H-purine 
• 851370-52-0 2-(benzylsulfanyl)-6-(3-chlorophenylamino)-9-isopropylpurine 
• 851370-53-1 2-(benzylsulfonyl)-6-(3-chlorophenylamino)-9-isopropylpurine 
• 1373822-52-6 4-(2-(benzylthio)-7-(2-(4-chlorophenoxy)ethyl)-6-oxo-6,7-dihydro-1Hpurin-8-yl)benzylphosphonic acid 
• 1373822-43-5 methyl hydrogen 4-(2-(benzylthio)-7-(2-(4-chlorophenoxy)ethyl)-6-oxo-6,7-dihydro-1H-purin-8-yl)benzylphosphonate 
• 1373822-42-4 diethyl 4-(N-(4-amino-2-(benzylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-N-(2-(4-chlorophenoxy)ethyl)carbamoyl)benzylphosphonate 
• 1373822-41-3 6-amino-2-(benzylthio)-5-(2-(4-chlorophenoxy)ethylamino)-pyrimidin-4(3H)-one 
• 1373822-48-0 4-(2-(benzylthio)-7-(2-(4-chlorophenoxy)ethyl)-6-oxo-6,7-dihydro-1H-purin-8-yl)benzoic acid 
• 1373822-47-9 methyl 4-(2-(benzylthio)-7-(2-(4-chlorophenoxy)ethyl)-6-oxo-6,7-dihydro-1H-purin-8-yl)benzoate 
• 1308253-41-9 2-(benzylsulfanyl)-N-(4-ethylphenyl)-6,7-dimethyl-4-pteridinamine 
• 1308253-40-8 2-(benzylsulfanyl)-6,7-dimethyl-N-(4-methylphenyl)-4-pteridinamine 
• 1308253-38-4 2-(benzylsulfanyl)-6,7-dimethyl-4-(1-pyrrolidinyl)pteridine 

Relevant articles and documents

New results on the reactivity of 5,6-diamino-4-hydroxy-2-mercaptopyrimidine

The reaction of 5,6-diamino-4-hydroxy-2-mercaptopyrimidine with mono- and α,ω-dihalocompounds has been reinvestigated. Alkyl derivatives of 5-amino group, not previously described, have been obtained as reaction products. A comparison with the reactivity of 6-amino-4-hydroxy-2- mercaptopyrimidine has been also performed.

Preliminary finding on a new calcium channel entry blocker chemotype: 5,6-diamino-4-hydroxy-2-mercaptopyrimidine derivatives

We report the preliminary in vitro characterization of a series of pyrimidines as a new chemotype that modulates cardiovascular parameters and relaxes ileum smooth muscle according to classical calcium entry blockers. Tested compounds showed an interestin

Syntheses of highly functionalised 6-substituted pteridines.

Methods for the synthesis of polyfunctional 6-substituted pteridines from the corresponding 6-aldehydes are described. Alkene, ester, ketone, amide, cyano, oxime, bromo, methoxy and dihydroxy functional groups have all been introduced principally through