54810-03-6

Basic information

• Product Name: phenanthridine-6(5H)-thione
• Synonyms: 6(5H)-phenanthridinethione; 6-phenanthridinethiol; Phenanthridine-6(5H)-thione
• CAS NO: 54810-03-6
• Molecular Formula: C₁₃H₉NS
• Molecular Weight: 211.2823
• Mol File: 54810-03-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 397.5°C at 760 mmHg
• Flash Point: 194.2°C
• Density: 1.31g/cm³
• Vapor Pressure: 1.58E-06mmHg at 25°C
• Refractive Index: 1.742
• CAS DataBase Reference: phenanthridine-6(5H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: phenanthridine-6(5H)-thione(54810-03-6)
• EPA Substance Registry System: phenanthridine-6(5H)-thione(54810-03-6)

Safety Data

• Hazardous Substances Data: 54810-03-6(Hazardous Substances Data)

Upstream product

• 19394-61-7 2-biphenylyl isothiocyanate 
• 66003-76-7 Diphenyliodonium triflate 
• 58109-40-3 diphenyliodonium hexafluorophosphate 

Downstream Products

• 46493-82-7 6-(Methylthio)-phenanthridin 

Relevant articles and documents

TfOH-Promoted Transition-Metal-Free Cascade Trifluoroethylation/Cyclization of Organic Isothiocyanates by Phenyl(2,2,2-trifluoroethyl)iodonium Triflate

An efficient and transition-metal-free method for the synthesis of the structurally diversified trifluoroethylthiol phenanthridines and 3,4-dihydroisoquinolines is described. Various 2-isothiocyanobiaryls and aryl alkyl isothiocyanates reacted with phenyl(2,2,2-trifluoroethyl)iodonium triflate in CH2Cl2 in the presence of trifluoromethanesulfonic acid at 40 °C to form the corresponding trifluoroethylation/cyclization products in good to quantitative yields. This work represents the first construction of trifluoroethylthiol phenanthridine and isoquinoline derivatives from isothiocyanates in the absence of transition-metal catalysts by a one-pot procedure.