54810-82-1

Basic information

• Product Name: 3,5-Dimethylbiphenyl-4-amine
• Synonyms: 3,5-Dimethylbiphenyl-4-amine
• CAS NO: 54810-82-1
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.2756
• Mol File: 54810-82-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 316.2°Cat760mmHg
• Flash Point: 150.9°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 0.000415mmHg at 25°C
• Refractive Index: 1.598
• PKA: 3.97±0.10(Predicted)
• CAS DataBase Reference: 3,5-Dimethylbiphenyl-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dimethylbiphenyl-4-amine(54810-82-1)
• EPA Substance Registry System: 3,5-Dimethylbiphenyl-4-amine(54810-82-1)

Safety Data

• Hazardous Substances Data: 54810-82-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H15N/c1-10-8-13(9-11(2)14(10)15)12-6-4-3-5-7-12/h3-9H,15H2,1-2H3

Upstream product

• 54810-87-6 3,5-dimethyl-4-nitro(1,1'-biphenyl) 
• 5152-80-7 N-(3,5-dimethyl-biphenyl-4-yl)-acetamide 
• 26334-20-3 2,6-dimethylphenylazide 
• 71-43-2 benzene 
• 5152-79-4 acetic acid-(N-chloro-2,6-dimethyl-anilide) 
• 32406-09-0 1,3-dimethyl-5-cyclohexylbenzene 
• 2198-53-0 N-(2,6-dimethylphenyl)acetamide 
• 87-62-7 2,6-dimethylaniline 
• 21436-98-6 2,6-dimethylaniline hydrochloride 
• 637-88-7 1,4-Cyclohexanedione 
• 24596-19-8 4-bromo-2,6-dimethylphenylamine 
• 98-80-6 phenylboronic acid 
• 2113-61-3 biphenyl-4-ylamine; hydrochloride 
• 67-56-1 methanol 

Downstream Products

• 756873-19-5 4-bromo-(3,5-dimethyl)biphenyl 
• 3419-44-1 2'',3',5',6''-Tetramethyl-p-quaterphenyl 
• 54810-84-3 p-Benzochinon-4(4'-phenyl-2'.6'-dimethylanil) 
• 54810-83-2 4,4'-Diphenyl-2,6,2',6'-tetramethyl-azobenzol 

Relevant articles and documents

SULFONAMIDES AS GPR40- AND GPR120-AGONISTS

The invention relates to compounds acting as agonists of G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40), and having formula (I). Said compounds are useful in the treatment of diseases or disorders modulated by GPR120 and/or GPR40 such as diabet

Room-temperature Suzuki-Miyaura cross-coupling reaction with α-diimine Pd(II) catalysts

An α-diimine Pd(II) complex containing chiral sec-phenethyl groups, {bis[N,N′-(4-methyl-2-sec-phenethylphenyl)imino]-2,3-butadiene}dichloropalladium (rac-C1), was synthesized and characterized. rac-C1 was applied as an efficient catalyst for the Suzuki-Miyaura cross-coupling reaction between various aniline halides and arylboronic acid in PEG-400-H2O at room temperature. Among a series of aniline halides, rac-C1 did not catalyze the cross-coupling of aniline chlorides and fluorides but efficiently catalyzed the cross-coupling of aniline bromides and iodides with phenylboronic acid. The catalytic activity reduced slightly with increasing steric hindrance of the aniline bromides. The complexes {bis[N,N′-(4-fluoro-2,6-diphenylphenyl)imino]-2,3-butadiene}dichloropalladium and {bis[N,N′-(4-fluoro-2,6-diphenylphenyl)imino]acenaphthene}dichloropalladium were also found to be efficient catalysts for the reaction.

NITROGENOUS HETEROCYCLIC DERIVATIVE HAVING 2,6-DISUBSTITUTED STYRYL

The invention provides a novel nitrogen-containing heterocyclic derivative having 2,6-disubstituted styryl and a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the nitrogen-containing heterocyclic derivative and a pharmaceutically acceptable salt thereof, in particular, a pharmaceutical composition effective as a sodium channel inhibitor, having an excellent analgesic action especially on neuropathic pain with minimized side effects.