54813-79-5Relevant academic research and scientific papers
ON THE REACTION OF INDOLE WITH SODIUM BOROHYDRIDE IN TRIFLUOROACETIC ACID
Gribble, Gordon W.,Nutaitis, Charles F.,Leese, Robert M.
, p. 379 - 386 (2007/10/02)
The reaction of indole (1) with sodium borohydride in trifluoroacetic acid gives, successively, indoline (3), N-(2,2,2-trifluoroethyl)indoline (4), and 1,1,1-trifluoro-2,2-bisethane (5), whose structure is established by chemical and spectral means.Similar reactions are observed with N-methylaniline (8) and anisole, but not with dibenzazepines 13 and 15, which give only N-trifluoroethylation.
