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α-(Chloroacetoxy)acetophenone, also known as 1-(chloroacetoxy)-4-methoxybenzene, is an organic compound with the chemical formula C9H9ClO3. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents. α-(chloroacetoxy)acetophenone is primarily used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. It is synthesized through the reaction of acetophenone with chloroacetic acid in the presence of a base, such as sodium hydroxide. Due to its reactivity, it is important to handle α-(chloroacetoxy)acetophenone with care, as it can be harmful if inhaled, ingested, or absorbed through the skin.

54821-88-4

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54821-88-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 54821-88-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,8,2 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 54821-88:
(7*5)+(6*4)+(5*8)+(4*2)+(3*1)+(2*8)+(1*8)=134
134 % 10 = 4
So 54821-88-4 is a valid CAS Registry Number.

54821-88-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-oxo-2-phenylethyl 2-chloroacetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54821-88-4 SDS

54821-88-4Relevant academic research and scientific papers

Phenacyl esters of acetic acid derivatives and their application for the synthesis of 2-oxo-4-phenyl-5-(phenylhydrazono)-2,5-dihydro-furan-3-derivatives

Melnicky, Radek,Kvapil, Lubomir,Slezar, Petr,Grepl, Martin,Hlavac, Jan,Lycka, Antonin,Hradil, Pavel

scheme or table, p. 1437 - 1443 (2009/04/07)

(Chemical Equation Presented) Coupling of various substituted phenacyl acetates 1 and diazonium salts 3 was studied. If the phenacyl acetates were substituted by an electronaceptor group such as CN or COOEt 3-substituted phenyl-5-(phenyl-hydrazono)-5H-fur

A New Base-labile Linker for Solid-phase Peptide Synthesis

Katti, Seturam B.,Misra, Pravin K.,Haq, Wahajul,Mathur, Krishna B.

, p. 843 - 844 (2007/10/02)

A new base labile and orthogonally compatible linker for use in solid-phase peptide synthesis is described.

Oxidation of Aryl Alkyl Ketones to α-Acyloxy, α-(Camphorsulfonyloxy), or α-Hydroxy Derivatives Using Manganese(III) Acetate in Combination with Carboxylic Acids or (1S)-(+)-10-Camphorsulfonic Acid

Demir, Ayhan S.,Camkerten, Nurettin,Akgun, Hulya,Tanyeli, Cihangir,Mahasneh, Ali S.,Watt, David S.

, p. 2279 - 2289 (2007/10/02)

The α-oxidation of aryl alkyl ketones using manganese(III) acetate in the presence of various carboxylic acids and (1S)-(+)-10-camphorsulfonic acid provided a convenient synthesis of α-acyloxy, α-(10-camphorsulfonyloxy), and α-hydroxy derivatives in good yield.

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