54833-65-7Relevant academic research and scientific papers
Synthesis of C3-Methyl-Substituted Pyrroloindolines and Furoindolines via Cascade Dearomatization of Indole Derivatives with Methyl Iodide
Yi, Ji-Cheng,Liu, Chuan,Dai, Li-Xin,You, Shu-Li
supporting information, p. 2975 - 2979 (2017/11/14)
A highly efficient method for constructing C3-methyl-substituted pyrroloindolines and furoindolines via cascade dearomatization reaction of indole derivatives with methyl iodide was developed. This protocol offers a direct approach to a wide range of C3 methyl substituted pyrroloindolines under mild conditions. The utility of this method was further demonstrated in the concise synthesis of (±)-esermethol.
Alkaloid synthesis via the intramolecular imidate methylide 1,3-dipolar cycloaddition reaction
Smith, Richard,Livinghouse, Tom
, p. 3559 - 3568 (2007/10/02)
A concise synthesis for the neurotoxic physostigmine alkaloid d,l-eserethole is described which relys upon an intramolecular cycloaddition reaction involving a "non-stabilized" imidate methylide and an unactivated alkene. The facility of this cyclization
