54835-24-4

Upstream product

• 50-00-0 formaldehyd 
• 99-91-2 para-chloroacetophenone 
• 109-89-7 diethylamine 
• 3946-29-0 3,4'-Dichloropropiophenone 

Downstream Products

• 92528-04-6 {[3-(4-Chloro-phenyl)-3-oxo-propyl]-methyl-amino}-acetic acid 
• 17935-48-7 DL-N-<β-(p-Chlorbenzoyl)-ethyl>-valin 
• 92515-06-5 2-[3-(4-Chloro-phenyl)-3-oxo-propylamino]-3-hydroxy-propionic acid 
• 92515-08-7 (2S,3R)-2-[3-(4-Chloro-phenyl)-3-oxo-propylamino]-3-hydroxy-butyric acid 
• 92515-04-3 (R)-2-[3-(4-Chloro-phenyl)-3-oxo-propylamino]-4-methyl-pentanoic acid 
• 92515-03-2 N-<β-(p-Chlorobenzoyl)ethyl>-L-leucine 
• 92515-10-1 N-<β-(p-Chlorobenzoyl)ethyl>-glycylglycine 
• 92515-12-3 (S)-2-[3-(4-Chloro-phenyl)-3-oxo-propylamino]-3-(1H-indol-3-yl)-propionic acid 

Relevant academic research and scientific papers

UROTENSIN II RECEPTOR MODULATORS

Disclosed are compounds of Formula I, or salts or prodrugs thereof, complexed with a human urotensin II receptor as defined herein. Also disclosed are compounds of Formula II, or salts or prodrugs thereof, as defined herein. Also disclosed are methods of modulating the activity of a urotensin II receptor using a compound of Formula I, or a compound of Formula II, or salts or prodrugs thereof. In addition, methods of treating diseases related to the activity of urotensin II receptors are disclosed.

Anticonvulsant activity of semicarbazone derivatives of Mannich bases

A series of semicarbazones of semicarbazide/p-chlorophenyl semicarbazide and Mannich bases of acetophenone/p-chloroacetophenone has been synthesized and their anticonvulsant activity screened against MES and scPTZ test. p-Chlorophenyl semi-carbazone of N,N-dimethylaminopropiophenone has been found to be the most active in all these tests.