54835-64-2 Usage
Uses
Used in Pharmaceutical Industry:
Daphneolone is used as an anti-inflammatory agent for its ability to inhibit COX-2, reducing the production of inflammatory prostaglandins and providing relief from inflammation.
Used in Oncology:
Daphneolone is used as an anticancer agent due to its antiproliferative effects on cancer cells, showing potential as a lead compound for developing novel anti-inflammatory and anticancer treatments.
Used in Antimicrobial Applications:
Daphneolone is used as an antimicrobial agent, leveraging its natural ability to combat bacteria and contributing to the development of new therapeutic agents for infectious diseases.
Used in Antifungal Applications:
Daphneolone is used as an antifungal agent, harnessing its potential to fight fungal infections and aiding in the discovery of new treatments for various fungal conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 54835-64-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,8,3 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 54835-64:
(7*5)+(6*4)+(5*8)+(4*3)+(3*5)+(2*6)+(1*4)=142
142 % 10 = 2
So 54835-64-2 is a valid CAS Registry Number.
54835-64-2Relevant academic research and scientific papers
Syntheses of the (+/-)--Gingerols (Pungent Principles of Ginger) and Related Compounds through Regioselective Aldol Condensations: Relative Pungency Assays
Dennif, Phillip,Macleod, Ian,Whiting, Donald A.
, p. 82 - 87 (2007/10/02)
The deprotonation of trimethylsilylzingerone (13) by lithium di-isopropylamide at -78 deg C has been found to be regioselective (92 : 8 in favour of less-substituted enolate): the anion was condensed with alkanals and acyl imidazoles to give convenient syntheses of (+/-)--- and --gingerols (1) and -, -, and -gingerdiones (9).Similary, 3-methoxy-4-trimethylsilyloxybenzylideneacetone (17) gave the (+/-)---dehydrogingerols (8) and -, -, and -dehydrogingerdiones (10).The aldol reaction to -gingerol and methyl -gingerol was also conducted through a vinyloxyborane or through the enol silyl ether (TiCl4 catalysis).Results of organoleptic assays on these compounds are discussed, and the relation between pungency in the gingerols and in capsaicin is commented on.The aldol method was also used to synthesise the natural β-ketols(+/-)-daphneolone (25) and (+/-)-hexahydrocurcumin (4).