54837-17-1Relevant articles and documents
Synthesis of Chiral Zileuton, A Potent And Selective Inhibitor Of 5-Lipoxygenase
Hsiao, Chi-Nung,Kolasa, Teodozyj
, p. 2629 - 2632 (2007/10/02)
Coupling and intramolecular Wittig reaction of N-benzyloxy-D-alanine anhydride (13) and (2-Mercaptophenyl)methyltriphenylphosphonium bromide (3) were used as key steps to prepare (+)-enantiomer of zileuton (1), a potent and selective inhibitor of 5-lipoxygenase.