54840-13-0

Upstream product

• 123-30-8 4-amino-phenol 
• 109-61-5 propoxycarbonyl chloride 

Downstream Products

• 102417-04-9 [4-(3-tert-Butylamino-2-hydroxy-propoxy)-phenyl]-carbamic acid propyl ester 
• 102417-03-8 [4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-carbamic acid propyl ester 
• 83263-97-2 (4-Oxiranylmethoxy-phenyl)-carbamic acid propyl ester 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of new β-adrenoreceptor antagonists. Evidence for the electrostatic requirements for β-adrenoreceptor antagonists

A series of mono- and disubstituted phenoxypropanolamines, structurally related to practolol and acebutolol, has been synthesized and tested for β-adrenoreceptor blocking activity. Structure-activity relationships are discussed. The reasons for the lack of activity of compounds 3n and 4n have also been examined. The results suggest that the negative electrostatic potential above the phenyl ring of phenoxypropanolamines is essential for binding activity and point to the presence of an electropositive residue in the β-adrenoreceptor binding site.

Ester of (alkynyloxy)-, (alkenyloxy)-, and (cyanoalkoxy) carbanilic acids and their use as herbicides

The invention is novel esters of (alkynyloxy)-, (alkenyloxy)-, and (cyanoalkoxy) carbanilic acids and the thiono and dithio derivatives of the carbanilic acids, and their use for controlling broadleaf weeds and grasses.