54844-23-4Relevant articles and documents
Synthesis and applications of tert-alkoxysiloxane linkers in solid-phase chemistry
Meloni, Marco M.,White, Peter D.,Armour, Duncan,Brown, Richard C.D.
, p. 299 - 311 (2007/10/03)
Straightforward syntheses of two tert-alkoxysilyl chloride functionalised resins 3 and 31 that allow facile attachment of 1°, 2°, 3° alcohols and phenols to the solid-phase have been achieved. Resin 3 displayed useful loading levels (0.7 mmol/g), and it was stable to storage in activated form. Siloxanes from reaction of 3 with alcohols and phenols were compatible with a variety of reaction conditions commonly used in solid-phase synthesis.
Stereoselective Aldol-Type Cyclization Reaction Mediated by Dibutylboron Triflate/Diisopropylethylamine
Das, Sanjib,Li, Lian-Sheng,Sinha, Subhash C.
, p. 123 - 126 (2007/10/03)
(Equation presented) Dibutylboron triflate/diisopropylethylamine mediated aldol-type cyclization provides an expedient route for the stereoselective synthesis of cyclic ethers in a single step. The method is highly efficient for the stereoselective synthe
Organotin-Mediated Monoacylation of Diols with Reversed Chemoselectivity: A Convenient Synthetic Method
Reginato, Gianna,Ricci, Alfredo,Roelens, Stefano,Scapecchi, Serena
, p. 5132 - 5139 (2007/10/02)
The organotin-mediated monoesterification of unsymmetrical diols with reversed chemoselectivity has been explored to ascertain scope and limits of the method and to provide an easy and convenient synthetic procedure.The reaction has been performed on a set of substituted diols with some acylating agents usually employed as protecting groups.Two different procedures have been devised to obtain either the desired diol monoesters directly or the corresponding trialkylsilyl ethers as protected derivatives.The latter provides a convenient approach to the preparation of easily interconvertible diol monoesters.Also, the reaction has been optimized as a one-pot procedure, avoiding the isolation and purification of the stannylated intermediates.The reversed monoesterification method has been successfully applied to 1,2-, 1,3-, and 1,4-diols of primary-secondary, primary-tertiary, and secondary-tertiary types and to ether functions containing 1,2-diols.Within its limits, the described method represents the first direct one-pot monoesterification of diols at the most substituted site, allowing some remarkable achievements as (a) an almost regiospecific reversed monobenzoylation of some 1,2-diols, (b) the selective acylation of the tertiary hydroxyl of a primary-tertiary diol, and (c) a highly selective preparation of secondary pivalate of primary-secondary diols.
SODIUM PERBORATE: A MILD AND CONVENIENT REAGENT FOR EFFICIENTLY OXIDIZING TRIALKYLBORANES
Kabalka, George W.,Shoup, Timothy M.,Goudgaon, Naganna
, p. 1483 - 1486 (2007/10/02)
Sodium perborate, a readily available and inexpensivereagent, efficiently oxidizes organoboranes.The reagent permits the oxidation of a wide variety of functionally substituted organoboranes.In nearly every instance, the product yields exceed those obtained using standard oxidation procedures.
Sodium Perborate: A Mild and Convenient Reagent for Efficiently Oxidizing Organoboranes
Kabalka, George W.,Shoup, Timothy M.,Goudgaon, Naganna M.
, p. 5930 - 5933 (2007/10/02)
Sodium perborate, a readily available and inexpensive reagent, efficiently oxidizes organoboranes.The reagent permits the oxidation of a wide variety of functionally substituted organoboranes.In nearly every instance, the product yields exceed those obtained using standard oxidation procedures.
