54845-36-2

Basic information

• Product Name: 2-Chloro-1,3-diisopropylbenzene
• Synonyms: 2-Chloro-1,3-diisopropylbenzene
• CAS NO: 54845-36-2
• Molecular Formula: C12H17Cl
• Molecular Weight: 196.72
• Mol File: 54845-36-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 223.4°C at 760 mmHg
• Flash Point: 106.1°C
• Appearance: /
• Density: 0.976g/cm³
• Vapor Pressure: 0.144mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: 2-Chloro-1,3-diisopropylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-1,3-diisopropylbenzene(54845-36-2)
• EPA Substance Registry System: 2-Chloro-1,3-diisopropylbenzene(54845-36-2)

Safety Data

• Hazardous Substances Data: 54845-36-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H17Cl/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9H,1-4H3

Upstream product

• 24544-04-5 2,6-diisopropylbenzenamine 
• 544-16-1 n-Butyl nitrite 
• 110-71-4 1,2-dimethoxyethane 
• 123-91-1 1,4-dioxane 
• 60090-48-4 2,6-di(isopropyl)-N-methyleneaniline 

Downstream Products

• 99-62-7 1,3-diisopropylbenzene 
• 641-96-3 2,2'-diphenylbiphenyl 
• 1482498-21-4 2,6-diisopropyl-2'-phenylbiphenyl 
• 36919-88-7 2,2′-diisopropylbiphenyl 
• 1482498-20-3 2,2',6-trisopropylbiphenyl 
• 13049-35-9 1,1'-Biphenyl, 2,2'-diethyl 
• 1482498-19-0 2,6-diisopropyl-2'-ethylbiphenyl 
• 605-39-0 2,2'-dimethyl-1,1'-biphenyl 
• 1482498-18-9 2,6-diisopropyl-2'-methylbiphenyl 
• 1235963-96-8 2,2′-diisopropoxybiphenyl 
• 1482498-24-7 2,6-diisopropyl-2'-isopropoxybiphenyl 

Relevant articles and documents

An active, general, and long-lived palladium catalyst for cross-couplings of deactivated (hetero)aryl chlorides and bromides with arylboronic acids

An active, general, and long-lived palladium catalyst for Suzuki-Miyaura reactions of aryl and heteroaryl chlorides deactivated by steric hindrance, electron richness, and coordinating functional groups is reported. In reactions of arylbromide bearing two o-tert-butyl substituents, C(sp3)-H arylation of the tert-butyl group, rather than the Suzuki-Miyaura reaction, proceeded in excellent yield. The key to the success of the reactions was the development of biphenylene-substituted dicyclohexylruthenocenylphosphine (CyR-Phos) as a supporting ligand.

Diazotisation of aromatic amines and solvolysis of diazonium salts in ethylene glycol ethers

Aniline and unhindered alkyl-substituted anilines undergo solvolysis in dioxane and DME saturated with dry hydrogen chloride on diazotisation with isoamyl nitrite to give 2-(2-chloroethoxy)ethyl aryl ethers and 2-methoxyethyl aryl ethers respectively in 36-47% yields. 2,6-Dialkyl-substituted anilines give the corresponding chloro compounds as the major product along with the aryl ethers in lower yields. Diazotisation of aniline in ethylene glycol and monomethyl ethers of ethylene glycol and diethylene glycol gave the corresponding alcoholysis products in low yields. The solvolysis of aniline did not occur on diazotisation in diethyl ether or THF.

Sterically Congested Molecules, 11. The 2,6-Diisopropylphenyl Substituent at C=C and C=N Groups

Two series of new compounds with sterically shielded, sp2-hybridized C-α atoms are prepared from bromo(chloro)-2,6-diisopropylbenzene.The α-(2,6-diisopropylphenyl) substituent common to all of them is used as an NMR-spectroscopic indicator for