548461-35-4Relevant academic research and scientific papers
Observations on the modified wenker synthesis of aziridines and the development of a biphasic system
Buckley, Benjamin R.,Patel, Anish P.,Wijayantha
, p. 1289 - 1292 (2013/04/10)
A cheap and reliable process for the modified Wenker cyclization to afford aziridines has been achieved using biphasic conditions for a range of amino alcohol starting materials. A 100 mmol "one-pot" process has also been devised, and the enantiopurity of the starting amino alcohol is retained in the aziridine product.
Development of a [3+3] cycloaddition strategy toward functionalized piperidines
Hedley, Simon J.,Moran, Wesley J.,Price, David A.,Harrity, Joseph P. A.
, p. 4286 - 4292 (2007/10/03)
This paper describes a novel route to functionalized piperidines via a formal [3+3] cycloaddition reaction of activated aziridines and palladium-trimethylenemethane (Pd-TMM) complexes. The cycloaddition reaction generally proceeds enantiospecifically with
