548488-09-1Relevant articles and documents
Spirodiepoxide reaction with cuprates
Ghosh, Partha,Lotesta, Stephen D.,Williams, Lawrence J.
, p. 2438 - 2439 (2007/10/03)
The first example of transition-metal-mediated transformations of spirodiepoxides and the first general method for carbon-carbon bond formation using the spirodiepoxide functional group are reported. Organocopper-mediated addition to spirodiepoxides gives
[3 + 2] annulation of allylic silanes in acyclic stereocontrol: Total synthesis of (9S)-dihydroerythronolide A
Peng, Zhi-Hui,Woerpel
, p. 6018 - 6019 (2007/10/03)
The [3 + 2] annulation reactions of allylic silanes can be utilized to achieve acyclic stereocontrol. This method was employed as a key step in an enantioselective total synthesis of (9S)-dihydroerythronolide A. The key annulation reaction served to estab