548488-09-1

Upstream product

• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 548487-87-2 (2S,3R,4S,5R)-4-benzyloxy-2,4-dimethyl-5-(tert-butyldimethylsiloxy)heptane-1,3-diol 
• 933487-16-2 3-(tert-butyl-dimethyl-silanyloxy)-2-[2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-pentan-2-ol 
• 100-39-0 benzyl bromide 
• 933487-14-0 5-(tert-butyl-dimethyl-silanyloxy)-1,4-dihydroxy-2,4-dimethyl-heptan-3-one 
• 548488-03-5 (2R,3R,4R,5R)-2,4-dimethyl-4-dimethylphenylsilyl-5-ethyl-3-(p-methoxybenzyloxy)-2-(p-methoxybenzyloxymethyl)tetrahydrofuran 
• 548488-05-7 (2R,3R,4R,5R)-4-benzyloxy-2,4-dimethyl-5-ethyl-3-(p-methoxybenzyloxy)-2-(p-methoxybenzyloxymethyl)tetrahydrofuran 
• 548488-04-6 (2R,3R,4R,5R)-2,4-dimethyl-5-ethyl-4-hydroxy-3-(p-methoxybenzyloxy)-2-(p-methoxybenzyloxymethyl)tetrahydrofuran 
• 548488-08-0 2,2-dimethyl propionic acid (R)-[(1R,2R)-benzyloxy-1-methyl-tert-butyldimethylsiloxy-butyl]-2-methylallyl ester 
• 548488-21-7 (2S,3R,4R,5R)-3-acetoxy-4-dimethylphenylsilyl-2,4-dimethyl-5-ethyltetrahydrofuran-2-carboxylic acid ethyl ester 
• 548487-85-0 2,2-dimethyl propionic acid (2R,3R,4R,5R)-4-benzyloxy-2,4-dimethyl-5-ethyl-2-iodomethyltetrahydrofuran-3-yl ester 
• 548487-86-1 (3R,4S,5R)-4-benzyloxy-2,4-dimethyl-5-(tert-butyldimethylsiloxy)hept-1-en-3-ol 
• 548488-07-9 2,2-dimethyl propionic acid (R)-[(1R,2R)-1-benzyloxy-1-methyl-2-hydroxybutyl]-2-methylallyl ester 
• 548488-22-8 (2R,3R,4R,5R)-4-dimethylphenylsilyl-3-hydroxy-2-hydroxymethyl-2,4-dimethyl-5-ethyltetrahydrofuran 

Relevant academic research and scientific papers

Spirodiepoxide reaction with cuprates

The first example of transition-metal-mediated transformations of spirodiepoxides and the first general method for carbon-carbon bond formation using the spirodiepoxide functional group are reported. Organocopper-mediated addition to spirodiepoxides gives

[3 + 2] annulation of allylic silanes in acyclic stereocontrol: Total synthesis of (9S)-dihydroerythronolide A

The [3 + 2] annulation reactions of allylic silanes can be utilized to achieve acyclic stereocontrol. This method was employed as a key step in an enantioselective total synthesis of (9S)-dihydroerythronolide A. The key annulation reaction served to estab