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2-amino-4,6-dimethylpyrimidine-5-carboxylic acid is a pyrimidine derivative with the molecular formula C8H11N3O2, featuring a carboxylic acid functional group. This chemical compound is known for its potential applications in the pharmaceutical industry, where it serves as a building block in the synthesis of various drugs and as an intermediate in the production of other chemicals. Its unique structure and properties have garnered interest for its potential biological activities and therapeutic properties, making it a valuable compound in both the chemical and pharmaceutical sectors.

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  • 548773-13-3 Structure
  • Basic information

    1. Product Name: 2-amino-4,6-dimethylpyrimidine-5-carboxylic acid
    2. Synonyms: 2-amino-4,6-dimethylpyrimidine-5-carboxylic acid;2-Amino-4,6-dimethyl-5-pyrimidinecarboxylic acid
    3. CAS NO:548773-13-3
    4. Molecular Formula: C7H9N3O2
    5. Molecular Weight: 167.16526
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 548773-13-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-amino-4,6-dimethylpyrimidine-5-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-amino-4,6-dimethylpyrimidine-5-carboxylic acid(548773-13-3)
    11. EPA Substance Registry System: 2-amino-4,6-dimethylpyrimidine-5-carboxylic acid(548773-13-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 548773-13-3(Hazardous Substances Data)

548773-13-3 Usage

Uses

Used in Pharmaceutical Industry:
2-amino-4,6-dimethylpyrimidine-5-carboxylic acid is used as a building block for the synthesis of various drugs, contributing to the development of new therapeutic agents. Its presence in drug formulations is attributed to its ability to enhance the pharmacological properties of the final product.
Used as an Intermediate in Chemical Production:
In the chemical industry, 2-amino-4,6-dimethylpyrimidine-5-carboxylic acid is utilized as an intermediate in the production of other chemicals. Its role in chemical synthesis processes is crucial for creating a range of compounds with diverse applications.
Used in Research and Development:
2-amino-4,6-dimethylpyrimidine-5-carboxylic acid is employed in research settings to study its potential biological activities and therapeutic properties. Scientists are interested in exploring its interactions with biological systems and its potential to contribute to the discovery of new medicines and treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 548773-13-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,8,7,7 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 548773-13:
(8*5)+(7*4)+(6*8)+(5*7)+(4*7)+(3*3)+(2*1)+(1*3)=193
193 % 10 = 3
So 548773-13-3 is a valid CAS Registry Number.
InChI:InChI=1S/C7H9N3O2/c1-3-5(6(11)12)4(2)10-7(8)9-3/h1-2H3,(H,11,12)(H2,8,9,10)

548773-13-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-4,6-dimethylpyrimidine-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-Amino-4,6-dimethyl-5-pyrimidinecarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:548773-13-3 SDS

548773-13-3Downstream Products

548773-13-3Relevant articles and documents

Oximino-piperidino-piperidine-based CCR5 antagonists. Part 2: Synthesis, SAR and biological evaluation of symmetrical heteroaryl carboxamides

Palani, Anandan,Shapiro, Sherry,Clader, John W.,Greenlee, William J.,Vice, Susan,McCombie, Stuart,Cox, Kathleen,Strizki, Julie,Baroudy, Bahige M.

, p. 709 - 712 (2007/10/03)

The synthesis, SAR and biological evaluation of symmetrical amide analogues of our clinical candidate SCH 351125 are described. A series of potent and orally bioavailable CCR5 antagonists containing symmetrical 2,6-dimethyl isonicotinamides and 2, 6-dimethyl pyrimidines amides were generated with enhanced affinity for the CCR5 receptor.

Piperazine-based CCR5 antagonists as HIV-1 inhibitors. III: Synthesis, antiviral and pharmacokinetic profiles of symmetrical heteroaryl carboxamides

McCombie, Stuart W.,Tagat, Jayaram R.,Vice, Susan F.,Lin, Sue-Ing,Steensma, Ruo,Palani, Anandan,Neustadt, Bernard R.,Baroudy, Bahige M.,Strizki, Julie M.,Endres, Michael,Cox, Kathleen,Dan, Niya,Chou, Chuan-Chu

, p. 567 - 571 (2007/10/03)

The unsymmetrical nicotinamide-N-oxide moiety in compound 1 was replaced with symmetrical isonicotinamides as well as 4,6-dimethyl pyrimidine-5-carboxamides. Compound 16 from the latter set reduced the number of rotamers, improved potency of inhibiting UIV entry, slightly diminished the affinity for the muscarine receptors and showed very good oral absorption.

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