54895-26-0Relevant academic research and scientific papers
Conformationally-restricted arginine analogues as alternative substrates and inhibitors of nitric oxide synthases
Lee, Younghee,Marletta, Michael A.,Martasek, Pavel,Roman, Linda J.,Masters, Bettie Sue Siler,Silverman, Richard B.
, p. 1097 - 1104 (1999)
Conformationally restricted arginine analogues (1-5) were synthesized and found to be alternative substrates or inhibitors of the three isozymes of nitric oxide synthase (NOS). A comparison of k(cat)/K(m) values shows that (E)-3,4-didehydro-d,l-arginine (
