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3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE, also known as PNU-282987, is a chemical compound with significant potential in the pharmaceutical industry. It functions as a selective agonist for the alpha7 subtype of nicotinic acetylcholine receptors, which play a crucial role in cognitive function and memory regulation. 3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE's specificity for the alpha7 receptors positions it as a promising candidate for drug development, particularly in the area of neuropharmacology.

54906-42-2

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54906-42-2 Usage

Uses

Used in Neuropharmacology:
3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE is used as a therapeutic agent for neurological disorders, specifically targeting the alpha7 nicotinic acetylcholine receptors. Its application is aimed at enhancing cognitive function and memory, making it a potential treatment for conditions such as Alzheimer's disease and schizophrenia.
Used in Alzheimer's Disease Treatment:
In the field of neurology, 3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE is used as a potential therapeutic intervention for Alzheimer's disease. 3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE's ability to modulate the alpha7 nicotinic acetylcholine receptors may help alleviate cognitive decline and memory impairment associated with the disease.
Used in Schizophrenia Treatment:
3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE is also considered for use in the treatment of schizophrenia. Its interaction with the alpha7 nicotinic acetylcholine receptors could contribute to the amelioration of cognitive symptoms and other neurological manifestations of the disorder.
Used in Inflammatory and Autoimmune Disease Research:
Although still in the exploratory phase, 3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE has shown potential applications in the treatment of inflammatory and autoimmune diseases. Its role as an alpha7 nicotinic acetylcholine receptor agonist suggests it may have immunomodulatory effects, which could be beneficial in managing such conditions.
Further research and clinical trials are essential to fully elucidate the pharmacological properties and medical applications of 3,4-DIHYDRO-2H-PYRROLO[1,2-A]PYRAZIN-1-ONE, ensuring its safe and effective use in various therapeutic areas.

Check Digit Verification of cas no

The CAS Registry Mumber 54906-42-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,9,0 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54906-42:
(7*5)+(6*4)+(5*9)+(4*0)+(3*6)+(2*4)+(1*2)=132
132 % 10 = 2
So 54906-42-2 is a valid CAS Registry Number.

54906-42-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-Dihydropyrrolo[1,2-a]pyrazin-1(2H)-one

1.2 Other means of identification

Product number -
Other names 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54906-42-2 SDS

54906-42-2Relevant academic research and scientific papers

Synthesis of 2-Methylpyrrolopyrazin-1(2H)-one

Brimble, Margaret A.,Brimble, Mark T.,Hodges, Richard,Lane, Geoffrey A.

, p. 1583 - 1590 (2007/10/02)

The synthesis of 2-methylpyrrolopyrazin-1(2H)-one (2) present in the insect feeding deterrent peramine (1) through oxidation of the saturated lactam (3) is described.The preparation of the related 6-methyl-1H-pyrrolopyridin-7(6H)-one (12) trough a Lewias-acid-catalysed cyclization of the amide acetal (7) is also described.

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